Integrative Medicine Research Lecture Series | NCCIH

Integrative Medicine Research Lecture Series | NCCIH





Dr. Christine Smolke's work related to yeast and opioid production has been prominently featured in scientific journals and the popular press. We are pleased that Dr. Smolke will be presenting at our next Integrative Medicine Lecture on Monday, April 4 at 9 a.m. on the NIH Campus, Lipsett Amphitheater (Bldg. 10). The lecture will also be videocast, so you can watch remotely.

The NCCIH Integrative Medicine Research Lecture Series provides overviews of the current state of research and practice involving complementary health approaches and explores perspectives on the emerging discipline of integrative medicine.

Videocast:  Watch online! Go to “Today's Events” at https://videocast.nih.gov/.

See NIH Visitor's Information

Upcoming Lectures

Topic: New Bio-Based Supply Chains for Medicines
Date: April 4, 2016 9:00 a.m. ET 
Speaker: Christina Smolke, Ph.D. 
Location: Masur Auditorium

 
Recent advances in synthetic biology are transforming our capacities to make things with biology. This bio-based manufacturing technology has the potential to be most disruptive around products for which existing material supply chains result in limited access. For example, broad access to medicines and the development of new medicines has been difficult to achieve, largely due to the coupling between material supply chains and these therapeutic compounds.

We are developing a biotechnology platform that will allow us to replace current supply chains for already-approved medicines with stable, secure, scalable, distributed, and economical microbial fermentation. Our initial target is the opioids, an essential class of medicines for pain management and palliative care, which are currently sourced through opium poppy cultivation. In addition, we will leverage this technology to access novel compound structural space that will open up tremendous opportunity for transforming the discovery and development of new drugs over a longer time frame.

Learning Objectives

• Describe at least three challenges that can be encountered in transferring plant natural product pathways to yeast.
• Describe at least two strategies that can be used to address these challenges.
• How might the reconstruction of complex plant pathways in yeast lead to the discovery of new medicines?

Biography

Christina D. Smolke, Ph.D., is an associate professor, associate chair of education, and W.M. Keck Foundation Faculty Scholar in the Department of Bioengineering and, by courtesy, Chemical Engineering at Stanford University.

Dr. Smolke’s research program develops foundational tools that drive transformative advances in our ability to engineer biology. For example, her group has led the development of a novel class of biological I/O devices, fundamentally changing how we interact with and program biology. Her group has also pioneered the development of microbial biosynthesis platforms for complex plant natural products, leading to disruptive technologies for sourcing and discovering medicines.

Dr. Smolke is an inventor on more than 15 patents and her research program has been honored with numerous awards, including Nature’s 10, the NIH Director’s Pioneer Award, the World Technology Award in Biotechnology, and the MIT Technology Review’s 35 Innovators Under 35 Award.

Topic: Fibromyalgia Integrative Training for Teens (FIT Teens): Development of a Novel Non-Pharmacologic Treatment for Juvenile Fibromyalgia
Date: June 6, 2016 10:00 a.m. ET 
Speaker: Susmita Kashikar-Zuck, Ph.D. 
Location: Lipsett Ampitheater