Genetics of Kidney Cancer (Renal Cell Cancer)–Health Professional Version (PDQ®)

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Changes to This Summary (02/23/2016)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Major Heritable Renal Cell Cancer Syndromes

Added Figure 1 depicting bilateral renal tumors in a patient with von Hippel-Lindau syndrome (VHL).

Added Figure 2 depicting brainstem and cerebellar hemangioblastomas in a patient with VHL.

Added Figure 3 depicting spinal hemangioblastomas in a patient with VHL.

Added Figure 4 depicting renal cell cancers in a patient with hereditary leiomyomatosis and renal cell cancer.

Revised text to state that fibrofolliculomas are suggestive of Birt-Hogg-Dubé syndrome (BHD).

Added Figure 5 depicting bilateral renal tumors in a patient with BHD.

This summary is written and maintained by the PDQ Cancer Genetics Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.

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