Childhood Cancer: Public Health and Genomic Insights - September 21, 2015

Genomics|Features|Childhood Cancer

Childhood Cancer

Childhood Cancer: Public Health and Genomic Insights - September 21, 2015

CDC Info

• Cancer prevention starts in childhood

For some children with cancer, genomic information may help guide treatment decisions, NCI, September 18, 2015

Improving patient outcomes with cancer genomics unique opportunities and challenges in pediatric oncology 
Schnepp RW et al. JAMA September 1, 2015

Integrative clinical sequencing in the management of refractory or relapsed cancer in youth 
Mody RJ et al. JAMA, September 1, 2015

How can precision medicine help children with cancer? By S Ravoori, AACR Blog Post, Jul 29

CDC information: Cancer prevention starts in childhood

Next-generation (epi)genetic drivers of childhood brain tumours and the outlook for targeted therapies.
Northcott PA et al. Lancet Oncol. 2015 Jun (6) e293-e302

Genetic susceptibility in childhood acute leukaemias: a systematic review.
Brisson GD et al. Ecancermedicalscience 2015 539

Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine.
Hunger SP et al. Blood 2015 Jun 25. (26) 3977-87

State of the art discovery with tumor profiling in pediatric oncology.
Carroll WL et al. Am Soc Clin Oncol Educ Book 2015 e601-7

Genomics in acute lymphoblastic leukaemia: insights and treatment implications.
Roberts KG et al. Nat Rev Clin Oncol 2015 Jun (6) 344-357

Childhood Cancer: Role of Genetics - January 20, 2015

NCI information for health professionals: Cancer in children and adolescents- The causes of most childhood cancers are not known. About 5 percent of all cancers in children are caused by an inherited mutation

Childhood cancers: Prevention, genetics, causes, from the National Cancer Institute

Pediatric Cancer Genome Project: Washington University St Louis and St Jude Hospital

Family cancer syndromes, from the American Cancer Society 

CDC information: Cancer prevention starts in childhood

Genetic and nongenetic risk factors for childhood cancer.
Spector LG,et al Pediatr Clin North Am. 2015 Feb;62(1):11-25

Going back to class I: MHC and immunotherapies for childhood cancer.
Haworth KB, et al. Pediatr Blood Cancer. 2014 Dec 18.

Neuroblastoma: Paradigm for precision medicine.
Irwin MS, et al. Pediatr Clin North Am. 2015 Feb;62(1):225-256

Retinoblastoma.
Rodriguez-Galindo C, et al. Pediatr Clin North Am. 2015 Feb;62(1):201-223.

Sarcomas.
HaDuong JH,et al. Pediatr Clin North Am. 2015 Feb;62(1):179-200

Brain Tumors.
Chintagumpala M, et al. Pediatr Clin North Am. 2015 Feb;62(1):167-178.