Pathogen Genomics & Public Health: The Time is Now
CDC 2013 accomplishments include using pathogen whole genome sequencing for the first time to clarify which patients' illnesses were related to an outbreak of listeriosis associated with consumption of contaminated cheese.
CDC information: New tools in pathogen genomics are changing the landscape in the fight against infectious diseases
Driving forward infectious disease genomics in the UK: Public Health England to launch a pathogen genomics service,
Christine McCartney, Dec 9
Christine McCartney, Dec 9CDC Public Health Grand Rounds Videocast: Advanced molecular detection (Dec 1)
CDC blog post: Genomes at CDC: Man, mouse an microbe-It’s a genomic world! (2013)
Pathogen Genomics
Pathogen Genomics for Public Health
The Centers for Disease Control and Prevention (CDC) is well known for its work in monitoring, investigating, and controlling infectious diseases in the United States and worldwide. Genetic information from viruses, bacteria, and other infectious organisms has long played a crucial role in these efforts.
Advances in molecular technologies and bioinformatics have made it possible to examine pathogen genomes in much greater detail. Now, falling cost and turnaround time are bringing high-throughput genetic sequencing within reach for use by clinical and public health investigators.
Public health applications of pathogen genomics include:
- Diagnosing infection (Legionella
- Investigating outbreaks (Listeria
- Describing transmission patterns (Tuberculosis
- Monitoring antimicrobial resistance (HIV
- Developing interventions, including vaccines (Influenza
CDC’s Advanced Molecular Detection (AMD) Initiative 
[PDF 392.40 KB] aims to build critical molecular sequencing and bioinformatics capacities at national and state levels to support public health efforts to control infectious diseases. For additional information, see the A New Landscape for Combatting Infectious Diseases [PDF 693.38 KB].
[PDF 392.40 KB] aims to build critical molecular sequencing and bioinformatics capacities at national and state levels to support public health efforts to control infectious diseases. For additional information, see the A New Landscape for Combatting Infectious Diseases [PDF 693.38 KB].OPHG blog posts on pathogen genomics:
Genomes at CDC: Man, mouse, and microbe—it's a genomic world! (May 23, 2013)
Now watch this: Genomic epidemiology (September 6, 2012)
No genome is an island (January 12, 2012)
Genome vs. genome: E. coli sprouts in Germany (June 30, 2011)
Now watch this: Genomic epidemiology (September 6, 2012)
No genome is an island (January 12, 2012)
Genome vs. genome: E. coli sprouts in Germany (June 30, 2011)
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