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Recurrent Nephrolithiasis in Adults: Comparative Effectiveness of Preventive Medical Strategies - Research Review - Final | AHRQ Effective Health Care Program
Increased fluid intake, reduced soft drink consumption, thiazide diuretics (which lower urinary calcium excretion and prevent calcium-containing kidney stones), citrate pharmacotherapy (citrate naturally prevents kidney stone formation), and allopurinol (used to treat excess uric acid in blood plasma) each decreased the risk of recurrent calcium kidney stones, according to a new research review by AHRQ’s Effective Health Care Program. Nephrolithiasis is the clinical term for the formation of hard masses, usually made of calcium crystals, in the kidneys. The research review, Recurrent Nephrolithiasis in Adults: Comparative Effectiveness of Preventive Medical Strategies, summarizes evidence on the effectiveness and risks of dietary and pharmacological preventive treatments for patients with nephrolithiasis.