Year-long trial finds NAD-boosting supplement fails to improve early Parkinson's symptoms (+++ +++ +++ +++)

Year-long trial finds NAD-boosting supplement fails to improve early Parkinson's symptoms https://www.news-medical.net/news/20261012/Year-long-trial-finds-NAD-boosting-supplement-fails-to-improve-early-Parkinsons-symptoms.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Year-long trial finds NAD-boosting supplement fails to improve early Parkinson's symptomsIn a phase 3 randomized clinical trial involving 410 people with early Parkinson disease, 52 weeks of nicotinamide riboside supplementation increased blood NAD levels but failed to improve clinical outcomes compared with placebo. Participants receiving the supplement had modestly worse overall disease scores, although the difference was below the threshold generally considered clinically meaningful. People who walk more each day tend to score better on several brain tests https://www.news-medical.net/news/20261014/People-who-walk-more-each-day-tend-to-score-better-on-several-brain-tests.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 People who walk more each day tend to score better on several brain testsResearchers analyzed 14 years of physical activity and blood pressure records from 3,093 US adults and found that higher daily step counts were associated with better performance on tests of attention, cognitive control, and reward-related decision-making. Higher systolic blood pressure was associated with poorer delay-discounting performance, but accounted for only 4. Epilepsy linked to higher risk of young-onset dementia https://www.news-medical.net/news/20261014/Epilepsy-linked-to-higher-risk-of-young-onset-dementia.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Epilepsy linked to higher risk of young-onset dementiaPeople with epilepsy may be more likely to develop young-onset dementia than people without epilepsy, according to a study published October 14, 2026, in Neurology®, the medical journal of the American Academy of Neurology. Hybrid AI architecture improves seizure prediction using EEG signals https://www.news-medical.net/news/20261013/Hybrid-AI-architecture-improves-seizure-prediction-using-EEG-signals.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Hybrid AI architecture improves seizure prediction using EEG signalsEpilepsy affects about 50 million people worldwide and can seriously affect patients' quality of life. Electroencephalography (EEG), which records the brain's electrical activity in real time, plays an important role in epilepsy diagnosis and monitoring. Recurrent brain tumors undergo unique genetic changes after treatment https://www.news-medical.net/news/20261014/Recurrent-brain-tumors-undergo-unique-genetic-changes-after-treatment.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Recurrent brain tumors undergo unique genetic changes after treatmentWhen patients are diagnosed with certain brain tumors, one of the biggest unanswered questions is what happens when the cancer returns. 16-year study links worsening vision to higher dementia risk https://www.news-medical.net/news/20261011/16-year-study-links-worsening-vision-to-higher-dementia-risk.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 16-year study links worsening vision to higher dementia riskResearchers followed 15,576 older adults in Hong Kong for up to 16 years and linked moderate to severe visual impairment to higher dementia risk, with rapid visual decline strengthening the association at poorer levels of vision. They estimated that severe impairment corresponded to 2.1 fewer dementia-free years over the study period, but could not establish that correcting vision prevents dementia. Study finds both the liver and brain drive distinct symptoms of rare genetic epilepsy https://www.news-medical.net/news/20261009/Study-finds-both-the-liver-and-brain-drive-distinct-symptoms-of-rare-genetic-epilepsy.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Study finds both the liver and brain drive distinct symptoms of rare genetic epilepsyA recent study from Johns Hopkins Medicine reveals that both the liver and brain contribute pathways to differing symptoms of the same rare inherited disorder. Routine blood test may offer clues to future dementia risk https://www.news-medical.net/news/20261009/Routine-blood-test-may-offer-clues-to-future-dementia-risk.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Routine blood test may offer clues to future dementia riskA common blood test already carried out during routine health checks may contain clues about a person's long-term risk of dementia, according to research being presented at the ECNP Congress in Munich and recently published in the Journal of Alzheimer's Disease. Study uncovers a protective role for microglia in Parkinson's disease https://www.news-medical.net/news/20261007/Study-uncovers-a-protective-role-for-microglia-in-Parkinsons-disease.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Study uncovers a protective role for microglia in Parkinson's diseaseResearchers at the University of Oxford have uncovered a previously unrecognized protective role for microglia, the brain's resident immune cells, in Parkinson's disease. Study reveals how different plant saponins alleviate ischemic stroke https://www.news-medical.net/news/20261012/Study-reveals-how-different-plant-saponins-alleviate-ischemic-stroke.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Study reveals how different plant saponins alleviate ischemic strokeIschemic stroke accounts for approximately 85% of all strokes and remains a major cause of death and long-term disability. Study links abnormal immature astroglia to lower fluid intelligence in older epilepsy patients https://www.news-medical.net/news/20261020/Study-links-abnormal-immature-astroglia-to-lower-fluid-intelligence-in-older-epilepsy-patients.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Study links abnormal immature astroglia to lower fluid intelligence in older epilepsy patientsA new USC-led study links abnormal immature astroglia, star-shaped cells that support brain function, to lower fluid intelligence, or the ability to solve new problems, in older adults with epilepsy. Adults with ADHD face higher risk of developing dementia later in life https://www.news-medical.net/news/20261007/Adults-with-ADHD-face-higher-risk-of-developing-dementia-later-in-life.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Adults with ADHD face higher risk of developing dementia later in lifeA new study led by University of Pittsburgh School of Medicine researchers finds that adults with attention-deficit/hyperactivity disorder (ADHD) face a significantly higher risk of developing dementia or mild cognitive impairment later in life.