Cortisol Excess Severity May Help Predict Recurrence and Progression in Adrenocortical Carcinoma ++++

https://www.medscape.com/viewarticle/cortisol-excess-severity-may-help-predict-recurrence-and-2026a1000z3t?src= Higher urinary free cortisol (UFC) levels at diagnosis were associated with an increased risk for tumor recurrence or progression in patients with Cushing syndrome (CS) secondary to adrenocortical carcinoma (ACC), according to a multicenter international cohort study of 101 patients. Both tumor size and UFC levels independently predicted metastatic disease at diagnosis. EMA Backs Three New Options in Lung and Ovarian Cancers Edited by Joyani Das https://www.medscape.com/viewarticle/ema-backs-three-new-options-lung-and-ovarian-cancers-2026a1000z3i?src= At its September 2026 meeting, European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended granting marketing authorization for three oncology medicines: Gevalka (ensartinib, SFL Pharmaceuticals), Lifyorli (relacorilant, Corcept Therapeutics), and Sepalna (senaparib, SFL Pharmaceuticals). The medicines address different stages of two solid tumor types: ALK-positive non-small cell lung cancer (NSCLC) and epithelial ovarian, fallopian tube, or primary peritoneal cancer. If approved by the European Commission, all three agents would be authorized across the EU... Quality of Life Preserved in Older Patients After Curative Treatment for Colorectal Cancer Metastases https://www.medscape.com/viewarticle/quality-life-preserved-older-patients-after-curative-2026a1000yjz?src= Older patients with metastatic colorectal cancer who received curative local surgical or ablative treatment for metastases maintained quality of life (QOL) over 12 months; physical functioning declined temporarily at 3 months but did not reach clinically relevant levels of decline at any timepoint. Digital Health Is Raising Patient Expectations Silvia C. Carpallo https://www.medscape.com/viewarticle/digital-health-raising-patient-expectations-2026a1000z20 Professional forums are increasingly focusing on how digital health can contribute to clinical workflows, from automating administrative tasks and analyzing imaging studies to segmenting patient groups. However, these discussions often overlook the role of patients and how digital health changes their expectations and perceptions of their healthcare needs.