Pim1 identified as promising therapeutic target for inflammatory arthritis treatment

https://www.news-medical.net/news/20260522/Pim1-identified-as-promising-therapeutic-target-for-inflammatory-arthritis-treatment.aspx The research team led by Professor Zhongyu Xie from Sun Yat-sen University revealed a new mechanism by which Pim1 regulated Th17 cell differentiation through mitochondrial metabolism. Through molecular docking screening, they identified Nilotinib as an effective candidate drug for the treatment of inflammatory arthritis by targeting Pim1. The relevant achievement has been published in Research (DOI: 10.34133/research.1137) with the title "Pim1 Serves as a Therapeutic Target for Inflammatory Arthritis via Mitochondrial Metabolism and Th17 Cell Differentiation."