Which Patients With Early HCC Should Undergo Resection? Daniela Barros l Medscape Europe May 29, 2026

https://www.medscape.com/viewarticle/which-patients-early-hcc-should-undergo-resection-2026a1000hwk For years, patients with early-stage hepatocellular carcinoma (HCC) who had multiple liver nodules were typically referred for less-invasive locoregional therapies such as radiofrequency ablation (RFA) and transarterial chemoembolization (TACE). The logic seemed sound: to avoid surgical trauma in people who often already have cirrhosis or limited liver function. Now, a new national multicenter meta-analysis suggests that, in carefully selected patients, this approach may need to be reconsidered.