Less Mental Decline With Darolutamide vs Enzalutamide in Prostate Cancer +++++

When the Defibrillator Stays in Its Box https://www.medscape.com/viewarticle/when-defibrillator-stays-its-box-2026a1000gjo?ecd=wnl_edit_tpal_etid8366046&uac=148436CN&impID=8366046 Playing for the Wycombe Wanderers' Foundation Under-19s on 31 January 2024, Adam Ankers, 17, went into sudden cardiac arrest towards the end of a match. He had shouted that his chest was tight moments before falling unconscious. Paramedics were called, but for 8 minutes no one on the pitch attempted CPR or used the defibrillator that had been brought out. A New Era for Locally Advanced NSCLC https://www.medscape.com/viewarticle/new-era-locally-advanced-nsclc-2026a1000fnu?ecd=wnl_edit_tpal_etid8366046&uac=148436CN&impID=8366046 Hello. It’s Mark Kris, from Memorial Sloan Kettering, speaking today about what I think is going to be a huge paradigm shift in the treatment of lung cancers, particularly locally advanced lung cancers. I’m going to call this, “The times they are a-changing: It’s time for a paradigm shift.” Less Mental Decline With Darolutamide vs Enzalutamide in Prostate Cancer https://www.medscape.com/viewarticle/less-mental-decline-darolutamide-vs-enzalutamide-prostate-2026a1000gg2?ecd=wnl_edit_tpal_etid8366046&uac=148436CN&impID=8366046 Darolutamide impairs cognitive function less than enzalutamide in men with advanced prostate cancer, according to a randomized trial with 111 patients. Patients completed five computerized tests from the Cambridge Neuropsychological Test Automated Battery to measure memory and thinking ability at baseline, 12 weeks, and 24 weeks. Researchers compared the results of the test with the greatest decline in each group at 24 weeks. Hematemesis and Heartburn in a Woman With a History of Heavy NSAID Use https://reference.medscape.com/viewarticle/hematemesis-and-heartburn-woman-history-heavy-nsaid-use-2026a1000fiv?ecd=wnl_edit_tpal_etid8366046&uac=148436CN&impID=8366046 The Case Challenge series includes difficult-to-diagnose conditions, some of which are not frequently encountered by most clinicians, but are nonetheless important to accurately recognize. Test your diagnostic and treatment skills using the following patient scenario and corresponding questions. If you have a case that you would like to suggest for a future Case Challenge, please email us at ccsuggestions@medscape.com with the subject line "Case Challenge Suggestion." How NPs Are Navigating Prior Authorization Coverage Barriers https://www.medscape.com/viewarticle/how-nps-are-navigating-prior-authorization-coverage-barriers-2026a1000gm0?ecd=wnl_edit_tpal_etid8366046&uac=148436CN&impID=8366046 Prior authorization requirements have become a defining feature of modern clinical practice, shaping not only treatment decisions but also the day-to-day workflow of clinicians. For nurse practitioners (NPs) and physician assistants (PAs), who increasingly serve on the front lines of patient care, the administrative burden associated with securing insurance approvals for medications, imaging, and specialty referrals can be substantial.