Background
- Since the time of ancient Greece, people have used grape products for health purposes.
- Today, grape seed extract is used as a dietary supplement for venous insufficiency (when veins have problems sending blood back from the legs to the heart) and other conditions.
How Much Do We Know?
- There are a few well-controlled studies in people on grape seed extract for health conditions.
What Have We Learned?
- Some studies suggest that compounds in grape seed extract may reduce swelling and help with symptoms of chronic venous insufficiency, but the evidence isn’t strong.
- Grape seed extract may lower systolic blood pressure and heart rate, but it does not affect cholesterol or other blood lipids.
What Do We Know About Safety?
- Grape seed extract is generally well tolerated when taken in moderate amounts. However, it may be unsafe for people who have bleeding disorders, who are going to have surgery soon, or who take anticoagulants (blood thinners).
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