sábado, 11 de julio de 2020

BMC Cancer | Home page

BMC Cancer | Home page



  1. Breast cancer is one of the most common tumors for women globally. Various miRNAs have been reported to play a crucial role in breast cancer, however the clinical significance of miR-1908-3p in breast cancer r...
    Authors:Youzhi Zhu, Qingshui Wang, Yun Xia, Xiaoxue Xiong, Shuyun Weng, Huizhen Ni, Yan Ye, Ling Chen, Junyu Lin, Yajuan Chen, Haitao Niu, Xiangjin Chen and Yao Lin
    Citation:BMC Cancer 2020 20:644
    Content type:Research article
     
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  2. For the first time, we present regional-level cancer incidence and world-standardized mortality rates for cancers for Martinique, Guadeloupe and French Guiana.
    Authors:Clarisse Joachim, Jacqueline Véronique-Baudin, Laure Desroziers, Édouard Chatignoux, Sophie Belliardo, Juliette Plenet, Jonathan Macni, Stephen Ulric-Gervaise, Jessica Peruvien, Bernard Bhakkan-Mambir and Jacqueline Deloumeaux
    Citation:BMC Cancer 2020 20:643
    Content type:Research article
     
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  3. The prognosis of patients with combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma (CHC) is usually poor, and effective adjuvant therapy is missing making it important to investigate whether ...
    Authors:Wei-Ren Liu, Meng-Xin Tian, Chen-Yang Tao, Zheng Tang, Yu-Fu Zhou, Shu-Shu Song, Xi-Fei Jiang, Han Wang, Pei-Yun Zhou, Wei-Feng Qu, Yuan Fang, Zhen-Bin Ding, Jian Zhou, Jia Fan and Ying-Hong Shi
    Citation:BMC Cancer 2020 20:642
    Content type:Research article
     
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  4. The COVID-19 pandemic has caused a global health crisis. Numerous cancer patients from non-Western countries, including the United Arab Emirates (UAE), seek cancer care outside their home countries and many ar...
    Authors:Humaid O. Al-Shamsi, Ibrahim Abu-Gheida, Shabeeha K. Rana, Neil Nijhawan, Ahmed S. Abdulsamad, Sadir Alrawi, Mohamed Abuhaleeqa, Taleb M. Almansoori, Thamir Alkasab, Essa M. Aleassa and Martine C. McManus
    Citation:BMC Cancer 2020 20:641
    Content type:Review
     
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  5. The skeleton is the first and most common distant metastatic site for breast cancer. Such metastases complicate cancer management, inducing considerable morbidities and decreasing patient survival. Osteomimeti...
    Authors:L. Absil, F. Journé, D. Larsimont, J. J. Body, L. Tafforeau and D. Nonclercq
    Citation:BMC Cancer 2020 20:640
    Content type:Research article
     
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  6. Sentinel lymph node is the first stop of lymphatic spreading of cancer with known primary. The lymph node metastasis pattern of cancer of unknown primary (CUP) is unclear and has been presumed to follow the sa...
    Authors:Yilin Shao, Xin Liu, Silong Hu, Yingjian Zhang, Wentao Li, Xiaoyan Zhou, Qifeng Wang, Yifeng Hou, Yong Chen, Yanli Wang, Yaohui Wang, Zhiguo Luo and Xichun Hu
    Citation:BMC Cancer 2020 20:639
    Content type:Research article
     
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  7. Many studies have found that use of aspirin can lengthen survival in patients with gastrointestinal cancer. The aim of this study was to assess the survival benefit of aspirin use compared with non-aspirin use...
    Authors:Ju-Li Lin, Jian-Xian Lin, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-bin Wang, Jun Lu, Qi-Yue Chen, Long-long Cao, Mi Lin and Chang-Ming Huang
    Citation:BMC Cancer 2020 20:638
    Content type:Research article
     
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  8. The incidence of thyroid cancer is increasing worldwide. This is not accompanied by a corresponding increase in mortality. In contrast, in most populations’ thyroid cancer mortality has been decreasing in rece...
    Authors:Enrique López Gavilanez, Noemí Bautista Litardo, Manuel Navarro Chávez, Mario Hernández Bonilla and Angel Segale Bajaña
    Citation:BMC Cancer 2020 20:637
    Content type:Correspondence
     
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  9. Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with a dismal response to single-use of immune checkpoint inhibitors (ICIs). ICIs combined with systemic therapy has shown efficacy and safety in vari...
    Authors:Lin Shui, Ke Cheng, Xiaofen Li, Pixian Shui, Xiaohan Zhou, Jian Li, Cheng Yi and Dan Cao
    Citation:BMC Cancer 2020 20:636
    Content type:Study protocol
     
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  10. In its 2006 report, From cancer patient to cancer survivor: lost in transition, the U.S. Institute of Medicine raised the need for a more coordinated and comprehensive care model for cancer survivors. Given the e...
    Authors:Barbara M. Wollersheim, Kristel M. van Asselt, Henk G. van der Poel, Henk C. P. M. van Weert, Michael Hauptmann, Valesca P. Retèl, Neil K. Aaronson, Lonneke V. van de Poll-Franse and Annelies H. Boekhout
    Citation:BMC Cancer 2020 20:635
    Content type:Study protocol
     
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  11. Drug resistance is a major cause of therapeutic failure that is often associated with elevated autophagy and apurinic/apyrimidinic endonuclease 1 (APE1) expression. Herein, we investigated the role of APE1 and...
    Authors:Shu-Ting Pan, Ji Zhou, Fang Yang, Shu-Feng Zhou and Tao Ren
    Citation:BMC Cancer 2020 20:634
    Content type:Research article
     
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  12. Pancreatic cancer has a poor prognosis and few choices of therapy. For patients with adequate performance status, FOLFIRINOX or gemcitabine plus nab-paclitaxel are preferred first-line treatment. 5-Fluorouraci...
    Authors:Zev A. Wainberg, Kynan Feeney, Myung Ah Lee, Andrés Muñoz, Antonio Cubillo Gracián, Sara Lonardi, Baek-Yeol Ryoo, Annie Hung, Yong Lin, Johanna Bendell and J. Randolph Hecht
    Citation:BMC Cancer 2020 20:633
    Content type:Research article
     
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  13. Chemokine (C-C motif) ligand 18 (CCL18) affects the malignant progression of varying cancers by activating chemokine receptors. Our previous work has shown that CCL18 promotes hyperplasia and invasiveness of o...
    Authors:Xiao Jiang, Zhijie Huang, Xiang Sun, Xianghuai Zheng, Jingpeng Liu, Jun Shen, Bo Jia, Haiyun Luo, Zhaoyi Mai, Guodong Chen and Jianjiang Zhao
    Citation:BMC Cancer 2020 20:632
    Content type:Research article
     
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  14. Spinal cord astrocytoma is a rare neoplasm, and patients usually recur within months after surgery. There is currently a lack of consensus regarding post-operative treatment. Clinical data on the activity of s...
    Authors:Jietao Lin, Ling Yu, Yuanfeng Fu, Hanrui Chen, Xinting Zheng, Shutang Wang, Chan Gao, Yang Cao and Lizhu Lin
    Citation:BMC Cancer 2020 20:630
    Content type:Case report
     
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  15. Acute myeloid leukemia (AML) is a heterogenous hematological malignancy with poor long-term survival. New drugs which improve the outcome of AML patients are urgently required. In this work, the activity and m...
    Authors:Hayaa Moeed Alhuthali, Tracey D. Bradshaw, Kuan-Hon Lim, Toh-Seok Kam and Claire H. Seedhouse
    Citation:BMC Cancer 2020 20:629
    Content type:Research article
     
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  16. Gastric cancer is the fifth most common cancer worldwide. Along with environmental factors, such as Helicobacter pylori (H. pylori) infection, genetic changes play important roles in gastric tumor formations. miR...
    Authors:Laleh Ebrahimi Ghahnavieh, Hossein Tabatabaeian, Zhaleh Ebrahimi Ghahnavieh, Mohammad Amin Honardoost, Mansoureh Azadeh, Mohamad Moazeni Bistgani and Kamran Ghaedi
    Citation:BMC Cancer 2020 20:621
    Content type:Research article
     
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  17. Oncolytic virotherapy is an upcoming treatment option for many tumor entities. But so far, a first oncolytic virus only was approved for advanced stages of malignant melanomas. Neuroendocrine tumors (NETs) con...
    Authors:Linus D. Kloker, Susanne Berchtold, Irina Smirnow, Julia Beil, Andreas Krieg, Bence Sipos and Ulrich M. Lauer
    Citation:BMC Cancer 2020 20:628
    Content type:Research article
     
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  18. Emerging evidence has demonstrated the limited access to metabolic substrates as an effective approach to block cancer cell growth. The mechanisms remain unclear. Our previous work has revealed that miR-221/22...
    Authors:Jinhui Lü, Chuyi Zhang, Junyi Han, Zhen Xu, Yuan Li, Lixiao Zhen, Qian Zhao, Yuefan Guo, Zhaohui Wang, Evelyne Bischof and Zuoren Yu
    Citation:BMC Cancer 2020 20:627
    Content type:Research article
     
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  19. The failure of treatment for breast cancer usually results from distant metastasis in which the epithelial-mesenchymal transition (EMT) plays a critical role. Hyperinsulinemia, the hallmark of Type 2 diabetes ...
    Authors:Baili Xia, Lijun Hou, Huan Kang, Wenhui Chang, Yi Liu, Yanli Zhang and Yi Ding
    Citation:BMC Cancer 2020 20:626
    Content type:Research article
     
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  20. Sarcomas are a heterogeneous group of malignancies arising from mesenchymal cells. Epidemiological studies on sarcoma from Australia are lacking, as previous studies have focused on a sarcoma type (e.g. soft t...
    Authors:Cameron M. Wright, Georgia Halkett, Richard Carey Smith and Rachael Moorin
    Citation:BMC Cancer 2020 20:625
    Content type:Research article
     
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  21. The oncogene LSF (encoded by TFCP2) has been proposed as a novel therapeutic target for multiple cancers. LSF overexpression in patient tumors correlates with poor prognosis in particular for both hepatocellular ...
    Authors:Jennifer L. S. Willoughby, Kelly George, Mark P. Roberto, Hang Gyeong Chin, Patrick Stoiber, Hyunjin Shin, Chandra Sekhar Pedamallu, Scott E. Schaus, Kevin Fitzgerald, Jagesh Shah and Ulla Hansen
    Citation:BMC Cancer 2020 20:552
    Content type:Research article
     
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  22. Clear cell renal cell carcinoma (ccRCC), the most aggressive renal cancer, is characterized by early lymph node metastases and bad prognosis. Most therapies targeting advanced or metastatic ccRCC are based, as...
    Authors:Marcela García, Maria Belen Palma, Jerome Verine, Santiago Miriuka, Ana M. Inda, Ana L. Errecalde, François Desgrandchamps, Edgardo D. Carosella and Diana Tronik-Le Roux
    Citation:BMC Cancer 2020 20:624
    Content type:Research article
     
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  23. The epidemiological features of Waldenström macroglobulinemia (WM) have seldom been investigated at a national level, particularly in East Asia. The goal of our study is to present the incidence, prevalence, m...
    Authors:Seri Jeong, Seom Gim Kong, Da Jung Kim, Sangjin Lee and Ho Sup Lee
    Citation:BMC Cancer 2020 20:623
    Content type:Research article
     
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  24. Patients with a metastatic breast cancer suffer from a deteriorated health-related quality of life and numerous symptoms such as pain, severe fatigue and a decrease of their physical fitness. As the feasibilit...
    Authors:Lidia Delrieu, Amélie Anota, Olivier Trédan, Damien Freyssenet, Aurélia Maire, Brice Canada, Baptiste Fournier, Olivia Febvey-Combes, Frank Pilleul, Amine Bouhamama, Christophe Caux, Florence Joly, Béatrice Fervers, Vincent Pialoux, David Pérol and Olivia Pérol
    Citation:BMC Cancer 2020 20:622
    Content type:Study protocol
     
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  25. Several studies have investigated the associations between the podocalyxin-like protein (PODXL) expression quantity or locations and cancers survival, but the results were far from conclusive. Therefore, we pr...
    Authors:Siying He, Wenjie Du, Menglan Li, Ming Yan and Fang Zheng
    Citation:BMC Cancer 2020 20:620
    Content type:Research article
     
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  26. We assessed the mechanism of hematopoietic stem cell (HSC) mobilization using etoposide with granulocyte-colony stimulating factor (G-CSF), and determined how this mechanism differs from that induced by cyclop...
    Authors:Ka-Won Kang, Seung-Jin Lee, Ji Hye Kim, Byung-Hyun Lee, Seok Jin Kim, Yong Park and Byung Soo Kim
    Citation:BMC Cancer 2020 20:619
    Content type:Research article
     
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  27. Despite an improvement of prognosis in breast and colon cancer, the outcome of the metastatic disease is still severe. Microevolution of cancer cells often leads to drug resistance and tumor-recurrence. To tar...
    Authors:Jérôme Ruhnau, Jonas Parczyk, Kerstin Danker, Britta Eickholt and Andreas Klein
    Citation:BMC Cancer 2020 20:617
    Content type:Research article
     
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  28. There is already evidence that the faecal immunochemical test (FIT) is a useful tool for the diagnosis of colorectal cancer (CRC) that helps to identify symptomatic patients requiring early colonoscopy. Althou...
    Authors:María Angeles Gutierrez-Stampa, Vanessa Aguilar, Cristina Sarasqueta, Joaquín Cubiella, Isabel Portillo and Luis Bujanda
    Citation:BMC Cancer 2020 20:616
    Content type:Research article
     
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  29. Breast cancer is a global health problem – it is the most common malignancy among women. Triple negative breast cancers (TNBC) account for 10–20% of female breast cancer. Most TNBC cases confer poor prognosis....
    Authors:Tamás Mezei, Melinda Hajdu, Gábor Czigléczki, Gábor Lotz, Judit Kocsis, Janina Kulka and Anna Horváth
    Citation:BMC Cancer 2020 20:615
    Content type:Case report
     
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  30. Microvascular invasion (MVI) is considered to be one of the important prognostic factors that affect postoperative recurrence in patients with hepatocellular carcinoma (HCC) with variable results across their ...
    Authors:Liming Wang, Weihu Wang, Weiqi Rong, Zhuo Li, Fan Wu, Yunhe Liu, Yiling Zheng, Kai Zhang, Tana Siqin, Mei Liu, Bo Chen and Jianxiong Wu
    Citation:BMC Cancer 2020 20:614
    Content type:Research article
     
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  31. Respiratory motion management with breath hold for patients with hepatobiliary cancers remain a challenge in the precise positioning for radiotherapy. We compared different image-guided alignment markers for e...
    Authors:Tzu-Jie Huang, Yun Tien, Jian-Kuen Wu, Wen-Tao Huang and Jason Chia-Hsien Cheng
    Citation:BMC Cancer 2020 20:613
    Content type:Research article
     
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  32. The clonoSEQ® Assay (Adaptive Biotechnologies Corporation, Seattle, USA) identifies and tracks unique disease-associated immunoglobulin (Ig) sequences by next-generation sequencing of IgH, IgK, and IgL rearran...
    Authors:Travers Ching, Megan E. Duncan, Tera Newman-Eerkes, Mollie M. E. McWhorter, Jeffrey M. Tracy, Michelle S. Steen, Ryan P. Brown, Srivatsa Venkatasubbarao, Nicholas K. Akers, Marissa Vignali, Martin E. Moorhead, Drew Watson, Ryan O. Emerson, Tobias P. Mann, B. Melina Cimler, Pamela L. Swatkowski…
    Citation:BMC Cancer 2020 20:612
    Content type:Research article
     
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  33. To explore the clinical value of texture analysis of MR images (multiphase Gd-EOB-DTPA-enhanced MRI and T2 weighted imaging (T2WI) to identify the differentiated degree of hepatocellular carcinoma (HCC).
    Authors:Mengmeng Feng, Mengchao Zhang, Yuanqing Liu, Nan Jiang, Qian Meng, Jia Wang, Ziyun Yao, Wenjuan Gan and Hui Dai
    Citation:BMC Cancer 2020 20:611
    Content type:Research article
     
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  34. Feasibility testing of a simultaneous sparing approach of hippocampus, hypothalamus and pituitary gland in patients undergoing whole-brain radiotherapy (WBRT) with and without a concomitant boost to metastatic...
    Authors:P. Mehta, S. Janssen, F. B. Fahlbusch, S. M. Schmid, J. Gebauer, F. Cremers, C. Ziemann, M. Tartz and D. Rades
    Citation:BMC Cancer 2020 20:610
    Content type:Research article
     
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  35. Chemotherapy induced cardio-toxicity has been recognized as a serious side effect since the first introduction to anthracyclines (ANT). Cardio-toxicity among patients with breast cancer is well studied but the...
    Authors:Sivan Shamai, Zach Rozenbaum, Ofer Merimsky, Matthew Derakhshesh, Yonatan Moshkovits, Joshua Arnold, Yan Topilsky, Yaron Arbel and Michal Laufer-Perl
    Citation:BMC Cancer 2020 20:609
    Content type:Research article
     
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  36. Considering that the knowledge of adenocarcinoma in villous adenoma of the colorectum is limited to several case reports, we designed a study to investigate independent prognostic factors and developed nomogra...
    Authors:Chao-Tao Tang, Ling Zeng, Jing Yang, Chunyan Zeng and Youxiang Chen
    Citation:BMC Cancer 2020 20:608
    Content type:Research article
     
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  37. Small hepatocellular carcinoma (sHCC) is a special subtype of HCC with the maximum tumor diameter ≤ 3 cm and excellent long-term outcomes. Surgical resection or radiofrequency ablation provides the greatest ch...
    Authors:Yi-hong Ling, Jie-wei Chen, Shi-hong Wen, Chao-yun Huang, Peng Li, Liang-he Lu, Jie Mei, Shao-hua Li, Wei Wei, Mu-yan Cai and Rong-ping Guo
    Citation:BMC Cancer 2020 20:607
    Content type:Research article
     
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  38. Cancer testis (CT) antigens are promising targets for cancer immunotherapies such as cancer vaccines and genetically modified adoptive T cell therapy. In this study, we evaluated the expression of three CT ant...
    Authors:Mikiya Ishihara, Shinichi Kageyama, Yoshihiro Miyahara, Takeshi Ishikawa, Shugo Ueda, Norihito Soga, Hiroaki Naota, Katsumi Mukai, Naozumi Harada, Hiroaki Ikeda and Hiroshi Shiku
    Citation:BMC Cancer 2020 20:606
    Content type:Research article
     
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  39. Little is known about the prevalence and incidence in low and middle-income countries (LMICs) of secondary lymphedema due to cancer. The purpose of the study is to estimate the prevalence and incidence in LMIC...
    Authors:Eric Torgbenu, Tim Luckett, Mark A. Buhagiar, Sungwon Chang and Jane L. Phillips
    Citation:BMC Cancer 2020 20:604
    Content type:Research article
     
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  40. Modulated electro-hyperthermia (mEHT) is a form of hyperthermia used in cancer treatment. mEHT has demonstrated the ability to activate host immunity by inducing the release of heat shock proteins, triggering ...
    Authors:I-Ming Kuo, Jih-Jong Lee, Yu-Shan Wang, Hsin-Chien Chiang, Cheng-Chung Huang, Pei-Jong Hsieh, Winston Han, Chiao-Hsu Ke, Albert T. C. Liao and Chen-Si Lin
    Citation:BMC Cancer 2020 20:603
    Content type:Research article
     
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  41. Esophageal squamous cell carcinoma (ESCC) is a common malignant carcinoma of digestive system with high mortality. RAB, member RAS oncogene family like 6 (RABL6), a member of the RAS subfamily, has been reported ...
    Authors:Yanfen Feng, Shumei Yan, Yuhua Huang, Qitao Huang, Fang Wang and Yiyan Lei
    Citation:BMC Cancer 2020 20:602
    Content type:Research article
     
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  42. Since body mass index (BMI) is a convincing risk factor for breast cancer, it is speculated to be associated with lymph node metastasis. However, epidemiological studies are inconclusive. Therefore, this study...
    Authors:Junyi Wang, Yaning Cai, Fangfang Yu, Zhiguang Ping and Li Liu
    Citation:BMC Cancer 2020 20:601
    Content type:Research article
     
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  43. Colorectal cancer (CRC) is a multifactorial disease resulting from both genetic predisposition and environmental factors including the gut microbiota (GM), but deciphering the influence of genetic variants, en...
    Authors:Jacob E. Moskowitz, Anthony G. Doran, Zhentian Lei, Susheel B. Busi, Marcia L. Hart, Craig L. Franklin, Lloyd W. Sumner, Thomas M. Keane and James M. Amos-Landgraf
    Citation:BMC Cancer 2020 20:600
    Content type:Research article
     
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  44. Lymph node metastasis is more likely in early-stage breast cancer with lower tumor-infiltrating lymphocyte (TIL) density. Therefore, we investigated the correlation between TILs and lymph node metastasis in cT...
    Authors:Koji Takada, Shinichiro Kashiwagi, Yuka Asano, Wataru Goto, Rika Kouhashi, Akimichi Yabumoto, Tamami Morisaki, Masatsune Shibutani, Tsutomu Takashima, Hisakazu Fujita, Kosei Hirakawa and Masaichi Ohira
    Citation:BMC Cancer 2020 20:598
    Content type:Research article
     
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  45. Soft-tissue metastasis (STM) is a relatively rare, but not exceptional, manifestation of lung cancer. The purpose of this study was to evaluate the imaging features of STM from lung cancer using fluorine-18 fl...
    Authors:Tingting Xu, Xinyi Zhang, Shumao Zhang, Chunfeng Liu, Wenhui Fu, Chengrun Zeng and Yue Chen
    Citation:BMC Cancer 2020 20:596
    Content type:Research article
     
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  46. Unlike other breast cancer subtypes that may be treated with a variety of hormonal or targeted therapies, there is a need to identify new, effective targets for triple-negative breast cancer (TNBC). It has rec...
    Authors:Gina Sizemore, Sarah McLaughlin, Mackenzie Newman, Kathleen Brundage, Amanda Ammer, Karen Martin, Elena Pugacheva, James Coad, Malcolm D. Mattes and Han-Gang Yu
    Citation:BMC Cancer 2020 20:595
    Content type:Research article
     
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  47. Patients with cancer have an increased risk of malnutrition which is associated with poor outcome. The Mini Nutritional Assessment (MNA®) is often used in older patients with cancer but its relation to outcome...
    Authors:G. Torbahn, T. Strauss, C. C. Sieber, E. Kiesswetter and D. Volkert
    Citation:BMC Cancer 2020 20:594
    Content type:Research article
     
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