Coronavirus Disease Portal|Home|PHGKB

Coronavirus Disease Portal|Home|PHGKB

 Spotlight on COVID-19

COVID-19 Disrupting Care for Nine of 10 People with Rare Condition
Global Genes, May 2020

As hospitals have curtailed services to focus on responding to the pandemic and minimizing the risk of infecting people, the survey found that six in 10 rare disease patients said they did not have access to medical therapies at home or at the hospital anymore, such as infusions, chemotherapy, and hormonal treatment.

Tracking the COVID-19 pandemic in Australia using genomics
T Seamann et al, MEDRXIV, May 16, 2020

Sequenced samples from Australia were representative of the global diversity of SARS-CoV-2, consistent with epidemiological findings of multiple importations and limited onward transmission. In total, 76 distinct genomic clusters were identified; these included large clusters and minimal intra-patient SARS-CoV-2 genomic diversity.

Modeling infectious disease dynamics
S Cobey, Science, May 15, 2020

The early spread of SARS-CoV-2 has revealed critical information about the potential size of the pandemic, if it were allowed to grow unchecked. This information has mathematical foundations developed from modeling other infectious diseases.

Wrong but Useful — What Covid-19 Epidemiologic Models Can and Cannot Tell Us
I Holmdahl et al, NEJM, May 15, 2020

Infectious disease modeling is an expansive field with a long history, encompassing a range of methods and assumptions that are not necessarily directly comparable, or even designed for the same purpose. There are five questions to ask about epidemiologic models.