martes, 25 de febrero de 2020

Ready, Set, Go: Immune System Status Predicts Future Responses | NIH: National Institute of Allergy and Infectious Diseases

Ready, Set, Go: Immune System Status Predicts Future Responses | NIH: National Institute of Allergy and Infectious Diseases

NIH: National Institute of Allergy and Infectious Diseases Logo

Top row of graphic labeled "High responder" shows a panel (left) of intensely colored cartoon immune cells producing many chemicals and a panel (right) depicting a robust immune response after a vaccine or disease flare. Bottom “low responder” row show a panel (left) of weakly colored cartoon immune cells producing few chemicals and a panel (right) depicting a weak immune response.

Ready, Set, Go: Immune System Status Predicts Future Responses

Identifying predictors of autoimmune disease flare-ups could aid treatment for these conditions by allowing doctors to intervene before symptoms worsen. Recognizing immune system attributes that forecast a healthy person’s response to vaccination or infection would help researchers develop new vaccines.
A new NIAID study connects these seemingly distinct avenues of research. Using publicly available data, NIAID scientists identified features of a person’s immune state at “baseline”—prior to vaccination for healthy people and during periods of remission for people with the autoimmune disease lupus—that predict later immune responses.
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