S100a4 upregulation in Pik3ca H1047R; Trp53 R270H; MMTV-Cre -driven mammary tumors promotes metastasis | Breast Cancer Research | Full Text

S100a4 upregulation in Pik3ca H1047R; Trp53 R270H; MMTV-Cre -driven mammary tumors promotes metastasis | Breast Cancer Research | Full Text

S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis

PIK3CA mutations are frequent in human breast cancer. Pik3caH1047R mutant expression in mouse mammary gland promotes tumorigenesis. TP53 mutations co-occur with PIK3CA mutations in human breast cancers. We previo...

Authors:Wenlin Yuan, Leonard D. Goldstein, Steffen Durinck, Ying-Jiun Chen, Thong T. Nguyen, Noelyn M. Kljavin, Ethan S. Sokol, Eric W. Stawiski, Benjamin Haley, James Ziai, Zora Modrusan and Somasekar Seshagiri

Citation:Breast Cancer Research 2019 21:152

Content type:Research article

Published on: 27 December 2019

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