viernes, 31 de enero de 2020

Cancer Cell International | Home page

Cancer Cell International | Home page



  1. Melanoma is one of the most aggressive tumors with the remarkable characteristic of resistance to traditional chemotherapy and radiotherapy. Although targeted therapy and immunotherapy benefit advanced melanom...
    Authors:Keke Li, Shuang Zhao, Jing Long, Juan Su, Lisha Wu, Juan Tao, Jianda Zhou, JiangLin Zhang, Xiang Chen and Cong Peng
    Citation:Cancer Cell International 2020 20:36
    Content type:Primary research
    Published on: 
  2. Radiation resistance is the main cause of recurrence after radiotherapy, and increased autophagy after radiotherapy is related to radiotherapy resistance. This study aims to investigate the reversal effect of ...
    Authors:Cong Wang, Yinli Yang, Lining Sun, Jing Wang, Zhansheng Jiang, Yanwei Li, Dongying Liu, Haiyan Sun and Zhanyu Pan
    Citation:Cancer Cell International 2020 20:35
    Content type:Primary research
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  3. Interleukin-24 (IL-24) is a therapeutic gene for melanoma, which can induce melanoma cell apoptosis. Mesenchymal stem cells (MSCs) show promise as a carrier to delivery anti-cancer factors to tumor tissues. Induc...
    Authors:Zheng Wu, Wei Liu, Zujia Wang, Baitao Zeng, Guangnan Peng, Hongyan Niu, Linlin Chen, Cong Liu, Qian Hu, Yuxuan Zhang, Mengmeng Pan, Lingqian Wu, Mujun Liu, Xionghao Liu and Desheng Liang
    Citation:Cancer Cell International 2020 20:33
    Content type:Primary research
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  4. Melanoma is notoriously resistant to current treatments, and less than 25% of metastatic melanoma cases respond to existing therapies. Growing evidence has shown that microRNAs (miRNAs) play a vital role in th...
    Authors:Chao Yang, Zeqiang Yan, Fen Hu, Wei Wei, Zhihua Sun and Wei Xu
    Citation:Cancer Cell International 2020 20:32
    Content type:Primary research
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  5. Circular RNAs (circRNAs) have received considerable attention in human cancer research. However, many circRNAs remain to be detected. In our study, we determined novel circRNAs and investigated their effects o...
    Authors:Hong-cheng Lu, Jia-qi Yao, Xiao Yang, Jie Han, Jing-zi Wang, Kun Xu, Rui Zhou, Hao Yu, Qiang Lv and Min Gu
    Citation:Cancer Cell International 2020 20:31
    Content type:Primary research
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  6. Colorectal cancer (CRC) is a complex and molecularly heterogeneous disease representing one of the most frequent causes of cancer-related death worldwide. About 8–15% of CRCs harbor a mutation in BRAF gene, a pro...
    Authors:Giuseppe Nicolò Fanelli, Carlo Alberto Dal Pozzo, Ilaria Depetris, Marta Schirripa, Stefano Brignola, Paola Biason, Mariangela Balistreri, Luca Dal Santo, Sara Lonardi, Giada Munari, Fotios Loupakis and Matteo Fassan
    Citation:Cancer Cell International 2020 20:30
    Content type:Review
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  7. Glioma is one of the most widely diagnosed malignancies worldwide. It has been reported that long noncoding RNAs (lncRNAs) are participators in the tumorgenesis of cancers. Nevertheless, the role and function ...
    Authors:Huixia Li, Tianhao Li, Dehai Huang and Peng Zhang
    Citation:Cancer Cell International 2020 20:29
    Content type:Primary research
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  8. Ubiquitin-specific protease 7 (USP7) is a de-ubiquitin enzyme that plays an essential role in multiple cancers and becomes a target for treatment. However, the role of USP7 and its therapeutic value for HCC re...
    Authors:Wei Zhang, Jingxin Zhang, Chenzhou Xu, Shiqing Zhang, Saiyan Bian, Feng Jiang, Wenkai Ni, Lishuai Qu, Cuihua Lu, Runzhou Ni, Yihui Fan, Mingbing Xiao and Jinxia Liu
    Citation:Cancer Cell International 2020 20:28
    Content type:Primary research
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  9. Clear cell renal cell carcinoma (ccRCC) comprises the majority of kidney cancer death worldwide, whose incidence and mortality are not promising. Identifying ideal biomarkers to construct a more accurate progn...
    Authors:Zedan Zhang, Enyu Lin, Hongkai Zhuang, Lu Xie, Xiaoqiang Feng, Jiumin Liu and Yuming Yu
    Citation:Cancer Cell International 2020 20:27
    Content type:Primary research
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  10. Therapeutic approaches for cancer rely on careful consideration of finding the optimal way of delivering the pro-drug for cellular-based cancer treatment. Cell lines and cell cultures have been used in these s...
    Authors:Jehad Zweiri and Stephen E. Christmas
    Citation:Cancer Cell International 2020 20:26
    Content type:Primary research
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  11. Circular RNAs (circRNAs) which are shown as a class of RNAs exhibit the importance in the regulation of gene expression and the development of biological process. However, the expression profile and molecular ...
    Authors:Zhen Zhang, Honglei Wu, Zhaosheng Chen, Guangchun Li and Bin Liu
    Citation:Cancer Cell International 2020 20:25
    Content type:Primary research
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  12. Increasing evidences have underlined the importance of long non-coding RNAs (lncRNAs) in human malignancies. LINC00958 has been found involved in some cancers. However, the underlying mechanical performance of...
    Authors:Longhai Yang, Lili Li, Zizi Zhou, Yi Liu, Jinyuan Sun, Xiaoming Zhang, Huiyu Pan and Song Liu
    Citation:Cancer Cell International 2020 20:24
    Content type:Primary research
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  13. Retinoblastoma (RB) is acknowledged to be the commonest intraocular malignancy in infants and children and the outcome of RB patients is unfavorable due to limited early diagnosis and effective therapy. SMAD f...
    Authors:Hui Wang and Xiang Ji
    Citation:Cancer Cell International 2020 20:23
    Content type:Primary research
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  14. Immune-related genes (IRGs) were linked to the prognosis of head and neck squamous cell carcinoma (HNSCC). This study aimed to identify the effects of an immune-related gene signature (IRGS) that can predict t...
    Authors:Yangyang She, Xiangbo Kong, Yaping Ge, Ping Yin, Zhiyong Liu, Jieyu Chen, Feng Gao and Silian Fang
    Citation:Cancer Cell International 2020 20:22
    Content type:Primary research
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  15. After publication of our article [1] it was highlighted by the authors that the type of this article was primary research, instead of review.
    Authors:Shengnan Zhang, Mengjuan Li, Fangfang Yuan, Lin Chen, Ruihua Mi, Xudong Wei, Yongping Song and Qingsong Yin
    Citation:Cancer Cell International 2020 20:21
    Content type:Correction
    Published on: 
    The original article was published in Cancer Cell International 2019 19:272
  16. The erythropoietin-producing hepatocellular (Eph) receptor A5 (EphA5) has been found to be overexpressed in some malignant tumors and is associated with disease prognosis. However, the role of EphA5 in esophag...
    Authors:Rui Zhang, Jing Liu, Wei Zhang, Lei Hua, Li-Ting Qian and Shao-Bing Zhou
    Citation:Cancer Cell International 2020 20:20
    Content type:Primary research
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  17. Preeclampsia (PE) is a prevalent pregnancy disorder that has been one of the leading causes of maternal and perinatal mortality worldwide. Circular RNAs (circRNAs) have recently considered as important regulat...
    Authors:Bing Zhou, Xia Zhang, Ting Li, Rongping Xie, Jianbin Zhou, Yu Luo and Chunfen Yang
    Citation:Cancer Cell International 2020 20:19
    Content type:Primary research
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  18. There are different treatments for breast cancer and melanoma that mostly have some side effects. One of the therapeutic strategies is the use of natural components. Phenol components are a class of antioxidan...
    Authors:Khatereh Khorsandi, Zahra Kianmehr, Zohreh hosseinmardi and Reza Hosseinzadeh
    Citation:Cancer Cell International 2020 20:18
    Content type:Primary research
    Published on: 
  19. Microtubule-associated proteins 7(MAP7) was reported to be engaged into the function of neuronal function. The function of MAP7 in human cervical cancer (CC) was unknown. We aimed to uncover the function and m...
    Authors:Li Zhang, Xudong Liu, Lina Song, Hui Zhai and Chaohua Chang
    Citation:Cancer Cell International 2020 20:17
    Content type:Primary research
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  20. The patients with high microsatellite instability (MSI-H)/mismatch repair deficient (dMMR) tumors recently have been reported that can benefit from immunotherapy, and MSI can be used as a genetic instability o...
    Authors:Kai Li, Haiqing Luo, Lianfang Huang, Hui Luo and Xiao Zhu
    Citation:Cancer Cell International 2020 20:16
    Content type:Review
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  21. To evaluate the prognostic value of pretreatment lymphocyte counts with respect to clinical outcomes in patients with solid tumors.
    Authors:Jiawen Zhao, Weijia Huang, Yongxian Wu, Yihuan Luo, Bo Wu, Jiwen Cheng, Junqiang Chen, Deyun Liu and Chengyang Li
    Citation:Cancer Cell International 2020 20:15
    Content type:Primary research
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  22. Increasing evidence has suggested that microRNAs (miRNAs) act as key post-transcriptional regulators in tumor progression. Previous studies have confirmed that miR-17-5p functions as an oncogene in multiple ca...
    Authors:Jian-Xing Wang, Xin-Ju Jia, Yan Liu, Jin-Hui Dong, Xiu-Min Ren, Ou Xu, Sheng-Hui Liu and Chun-Guang Shan
    Citation:Cancer Cell International 2020 20:14
    Content type:Primary research
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  23. microRNA Let-7 serves as a tumor suppressor by targeting various oncogenic pathways in cancer cells. However, the underlying mechanism of its involvement in breast cancer remains largely unknown. With our rese...
    Authors:Hongbin Wang, Yanlv Ren, Cheng Qian, Jiaxin Liu, Ge Li and Zhigao Li
    Citation:Cancer Cell International 2020 20:13
    Content type:Primary research
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  24. Melanoma is the most aggressive type of skin cancer with high mortality rate and poor prognosis. lncRNA MEG3, a tumor suppressor, is closely related to the development of various cancers. However, the role of ...
    Authors:Liangcai Wu, Lifei Zhu, Yanchang Li, Zhixin Zheng, Xi Lin and Chaoying Yang
    Citation:Cancer Cell International 2020 20:12
    Content type:Primary research
    Published on: 
  25. Rapid progression contributes to treatment failure in anaplastic thyroid carcinoma (ATC) patients. In a preliminary study, we demonstrated that some hematopoietic factors may be involved in the progression of ...
    Authors:Zhao-Ming Zhong, Xue Chen, Xiao Qi, Xue-Min Wang, Chun-Yan Li, Ru-Jia Qin, Shi-Qi Wang, Jin Liang, Mu-Sheng Zeng and Chuan-Zheng Sun
    Citation:Cancer Cell International 2020 20:11
    Content type:Primary research
    Published on: 
  26. Accumulating evidence has associated aberrant long non-coding RNAs (lncRNAs) with various human cancers. This study aimed to explore the role of LINC00908 in prostate cancer (PCa) and its possible underlying m...
    Authors:Li Fan, Hai Li and Yun Zhang
    Citation:Cancer Cell International 2020 20:10
    Content type:Primary research
    Published on: 
  27. Aurora kinase A (AURKA) has been implicated in the regulation of cell cycle progression, mitosis and a key number of oncogenic signaling pathways in various malignancies including neuroblastoma. Small molecule...
    Authors:Yan Yang, Lili Ding, Qi Zhou, Li Fen, Yuhua Cao, Junjie Sun, Xuefeng Zhou and Aiguo Liu
    Citation:Cancer Cell International 2020 20:9
    Content type:Primary research
    Published on: 
  28. Accumulating evidence indicates that the long noncoding RNA taurine upregulated gene 1(TUG1) plays a critical role in cancer progression and metastasis. However, the overall biological role and clinical signif...
    Authors:Qun Dai, Jingyi Deng, Jinrong Zhou, Zhuhong Wang, Xiao-feng Yuan, Shunwen Pan and Hong-bin Zhang
    Citation:Cancer Cell International 2020 20:8
    Content type:Primary research
    Published on: 
  29. CTLA-4 is a well-studied immune checkpoint protein that negatively regulates T cell-mediated immune responses. However, the expression of CTLA-4 in glioma and the effects of CTLA-4 on prognosis in patients wit...
    Authors:Fangkun Liu, Jing Huang, Xuming Liu, Quan Cheng, Chengke Luo and Zhixiong Liu
    Citation:Cancer Cell International 2020 20:7
    Content type:Primary research
    Published on: 
  30. LncRNA Brain Cytoplasmic RNA 1 (BCYRN1) has been certified to modulate cancer cells growth and aggressiveness in several tumors. However, research about function of BCYRN1 in hepatocellular carcinoma (HCC) is ...
    Authors:Shichao Ding, Yanfeng Jin, Qingzhi Hao, Yanmeng Kang and Ruiping Ma
    Citation:Cancer Cell International 2020 20:6
    Content type:Primary research
    Published on: 
  31. Ovarian cancer (OC) is a common fatal malignant tumor of female reproductive system worldwide. Growing studies have proofed that circular RNAs (circRNAs) engage in the regulation of various types of cancers. H...
    Authors:Wumei Lin, Haiyan Ye, Keli You and Le Chen
    Citation:Cancer Cell International 2020 20:5
    Content type:Primary research
    Published on: 
  32. The issue of drug resistance in gastric cancer has attracted global attention. TSPAN9, a 4-transmembrane protein that plays an important role in tumor progression and signal transduction, has been found to be ...
    Authors:Yaoyue Qi, Weiwei Qi, Shihai Liu, Libin Sun, Aiping Ding, Guohong Yu, Hui Li, Yixuan Wang, Wensheng Qiu and Jing Lv
    Citation:Cancer Cell International 2020 20:4
    Content type:Primary research
    Published on: 
  33. Ubiquilin-4 (UBQLN4) is a member of the ubiquitin–proteasome system that is usually upregulated in many tumor cells. Its overexpression has been associated with poor disease outcomes in various cancer diseases...
    Authors:Yan Yu, Penglin Xu, Guangying Cui, Xiaodong Xu, Kongfei Li, Xiaolong Chen and Jie Bao
    Citation:Cancer Cell International 2020 20:3
    Content type:Primary research
    Published on: 
  34. Lung adenocarcinoma (LUAD), a widespread histopathological subtype of lung cancer, is deemed as a malignant tumor with a peak risk of mortality. Emerged as RNA with a loop structure that depleted protein codin...
    Authors:Nan Gao and Baoguo Ye
    Citation:Cancer Cell International 2020 20:2
    Content type:Primary research
    Published on: 
  35. Gliomas account for the major part of primary brain tumors. Based on their histology and molecular alternations, adult gliomas have been classified into four grades, each with distinct biology and outcome. Pre...
    Authors:Wenxin Zeng, Zhaohua Tang, Yongguo Li, Guangnian Yin, Zili Liu, Jie Gao, Yan Chen and Feilan Chen
    Citation:Cancer Cell International 2020 20:1
    Content type:Primary research
    Published on: 
  36. Increasing studies have suggested that aberrant expression of microRNAs might play essential roles in the progression of cancers. In this study, we sought to construct a high-specific and superior microRNAs si...
    Authors:Rong Ma, Yanyun Zhao, Miao He, Hongliang Zhao, Yifan Zhang, Shuqi Zhou, Mengcong Gao, Di Di, Jue Wang, Jian Ding and Minjie Wei
    Citation:Cancer Cell International 2019 19:360
    Content type:Primary research
    Published on: 
  37. The editor has retracted this article [1] because Fig. 2f has been duplicated from Fig. 6j in a previously published article [2]. In addition, the article contains sections that substantially overlap with a pr...
    Authors:Jie Song, Wei Zhao, Chang Lu and Xue Shao
    Citation:Cancer Cell International 2019 19:359
    Content type:Retraction Note
    Published on: 
    The original article was published in Cancer Cell International 2019 19:60
  38. The editor has retracted this article [1] because Figures 2 and 4 contain duplicated and modified figures from [2–4]. The data reported in this article are therefore unreliable.
    Authors:Xiaoyan Ding, Wei Sun and Jinglong Chen
    Citation:Cancer Cell International 2019 19:358
    Content type:Retraction Note
    Published on: 
    The original article was published in Cancer Cell International 2018 18:176
  39. Neuroblastoma (NB) is one of most common childhood tumors with high mortality among children worldwide. microRNAs (miRNAs) have been reported to play essential roles in the pathogenesis and therapeutics of NB....
    Authors:Fengxia Mao, Ju Zhang, Xinru Cheng and Qianya Xu
    Citation:Cancer Cell International 2019 19:357
    Content type:Primary research
    Published on: 
  40. The DNA damage and repair pathway is considered a promising target for developing strategies against cancer. RAD51, also known as RECA, is a recombinase that performs the critical step in homologous recombinat...
    Authors:Xiaomeng Zhang, Ningyi Ma, Weiqiang Yao, Shuo Li and Zhigang Ren
    Citation:Cancer Cell International 2019 19:356
    Content type:Primary research
    Published on: 
  41. The purpose of this study was to build functional nomograms based on significant clinicopathological features to predict cause-specific survival (CSS) and overall survival (OS) in patients with stage I–III col...
    Authors:Zheng Zhou, Shaobo Mo, Weixing Dai, Wenqiang Xiang, Lingyu Han, Qingguo Li, Renjie Wang, Lu Liu, Long Zhang, Sanjun Cai and Guoxiang Cai
    Citation:Cancer Cell International 2019 19:355
    Content type:Primary research
    Published on: 
  42. miR-100 has been reported to closely associate with gastric cancer (GC) initiation and progression. However, the underlying mechanism of miR-100-3p in GC is still largely unclear. In this study, we intend to s...
    Authors:Chun-Wei Peng, Ling-Xiao Yue, Yuan-Qin Zhou, Sai Tang, Chen Kan, Lei-Ming Xia, Fan Yang and Si-Ying Wang
    Citation:Cancer Cell International 2019 19:354
    Content type:Primary research
    Published on: 
  43. Gastric cancer (GC) is a common-sighted cancer which is hard to cure over the world. Substantial researches revealed that long non-coding RNAs (lncRNAs) were fundamental regulators in the process of cancers. N...
    Authors:Zhaosheng Chen, Honglei Wu, Zhen Zhang, Guangchun Li and Bin Liu
    Citation:Cancer Cell International 2019 19:351
    Content type:Primary research
    Published on: 
  44. Gastric cancer (GC) is one common cancer which occurs in the stomach leading to high mortality around the world. Long non-coding RNAs (lncRNAs) were found overexpressed or silenced in the occurrence and progre...
    Authors:Hua Zhang, Haitao Huang, Xiaomei Xu, Haiying Wang, Jianxiang Wang, Zuoyi Yao, Xiaoyan Xu, Qian Wu and Fenlan Xu
    Citation:Cancer Cell International 2019 19:350
    Content type:Primary research
    Published on: 
  45. Over the years, long non-coding RNAs (lncRNAs) have been clarified in malignancies, this research was focused on the role of lncRNA cartilage injury-related (lncRNA-CIR) in osteosarcoma cells.
    Authors:Shiwei Liu, Jingchao Li, Liang Kang, Yueyang Tian and Yuan Xue
    Citation:Cancer Cell International 2019 19:349
    Content type:Primary research
    Published on: 
  46. Casticin, an isoflavone compound extracted from the herb Fructus Viticis, has demonstrated anti-inflammatory and anticancer activities and properties. The aim of this study was to investigate the effects and m...
    Authors:Jingxian Liu, Jinghong Yang, Yuhe Hou, Zhenwei Zhu, Jie He, Hao Zhao, Xidong Ye, Dengke Li, Zhaohui Wu, Zhongxi Huang, Bingtao Hao and Kaitai Yao
    Citation:Cancer Cell International 2019 19:348
    Content type:Primary research
    Published on: 
  47. Ovarian cancer (OC) is a gynecological malignancy with a high mortality. Cisplatin-based treatment is the typical treatment regimen for OC patients; however, it may cause unfavorable resistance. The current st...
    Authors:Hua Guo, Chunfang Ha, Hui Dong, Zhijuan Yang, Yuan Ma and Yonghui Ding
    Citation:Cancer Cell International 2019 19:347
    Content type:Primary research
    Published on: 

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