Can cells collected from bone marrow stimulate generation of new neurons in babies with CHD? | Children's National

Can cells collected from bone marrow stimulate generation of new neurons in babies with CHD? | Children's National

Can cells collected from bone marrow stimulate generation of new neurons in babies with CHD?

The NIH has awarded Children’s National Hospital $2.5 million to test the hypothesis that mesenchymal stromal cells, collected from allogeneic bone marrow, may promote regeneration of damaged neuronal and glial cells in the early postnatal brain. The study is a single-center collaboration between three Children’s National physician-researchers: Richard Jonas, M.D., Catherine Bollard, M.B.Ch.B., M.D. and Nobuyuki Ishibashi, M.D.

If successful, the trial will determine the safety of the proposed treatment in humans and set the stage for a Phase 2 efficacy trial of what could potentially be the first treatment for delays in brain development that happen before birth as a consequence of congenital heart disease.