martes, 28 de enero de 2020

DENDRO: genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing | Genome Biology | Full Text

DENDRO: genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing | Genome Biology | Full Text

Although scRNA-seq is now ubiquitously adopted in studies of intratumor heterogeneity, detection of somatic mutations and inference of clonal membership from scRNA-seq is currently unreliable. We propose DENDR...
Authors:Zilu Zhou, Bihui Xu, Andy Minn and Nancy R. Zhang
Citation:Genome Biology 2020 21:10
Content type:Method
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