lunes, 23 de septiembre de 2019

Medical News | Medical Articles: Pharmacokinetics of Cannabis and its Secondary Metabolites

Medical News | Medical Articles

 
 September 23, 2019 
 Cannabis Testing & Analysis 
 The latest cannabis testing & analysis news from News Medical 
 Pharmacokinetics of Cannabis and its Secondary MetabolitesPharmacokinetics of Cannabis and its Secondary Metabolites
 
Once Cannabis enters the body, it undergoes a variety of different biological pathways that allow for its therapeutic effects to arise. In order to gain a better understanding as to how Cannabis can be efficiently used for medicinal purposes, it is imperative to investigate its pharmacokinetic properties following consumption
 
   Smoking simulator captures synthetic cannabinoid combustion productsSmoking simulator captures synthetic cannabinoid combustion products
 
Researchers have developed a smoking simulator that enables the reliable detection of the combustion products formed when synthetic cannabinoids are smoked.
 
   Therapeutic Uses of CannabisTherapeutic Uses of Cannabis
 
To date, over 545 different compounds have been identified and isolated from the Cannabis sativa L. (Cannabaceae) plant, of which include over 100 different cannabinoids. These compounds differ greatly in their chemical structure; thus, consumption of the cannabis plant can induce a wide range of effects.
 
 Crystal Structure of the Human Cannabinoid Receptor CB2
 
Crystal Structure of the Human Cannabinoid Receptor CB2Phytocannabinoids in the form of Cannabis plant is widely consumed by humans. Two of the cannabinoid receptors, CB1 and CB2 are the key targets of this endocannabinoid system.
 
 
 Cannabis use may alter gene linked to autism in male sperm
 
Cannabis use may alter gene linked to autism in male spermResearchers from Duke University Medical centre, Durham, USA have come up with an important study that shows that use of cannabis among men could alter a specific gene in their sperm that is linked to autism. The study titled, “Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm,” and is published in the latest issue of the journal Epigenetics.
 
 
 Accelerating drug discovery process to help patients
 
Accelerating drug discovery process to help patientsAn international research team has developed a new strategy that can predict the potential clinical implications of new therapeutic compounds based on simple cellular responses.
 
 
 Fatty foods increase CBD absorption, finds new research
 
Fatty foods increase CBD absorption, finds new researchWith both marijuana and alcohol being legal in the US, researchers have found that an increasing proportion of people are using both drugs in combination. However, this is a risky thing to do, says a new study. The increased risk is largely due to the overlap of effects between the two separate drugs.
 

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