Precision Medicine for Insomnia.

Boland E1, Goldschmied J2, Kayser MS2, Gehrman PR3.

Author information

1: Department of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, 3535 Market Street, Suite 670, Philadelphia, PA 19104, USA; Michael J. Crescenz VA Medical Center, MIRECC, 2nd Floor, B229 3900 Woodland Ave., Philadelphia, PA 19104, USA.
2: Department of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, 3535 Market Street, Suite 670, Philadelphia, PA 19104, USA.
3: Department of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, 3535 Market Street, Suite 670, Philadelphia, PA 19104, USA; Michael J. Crescenz VA Medical Center, MIRECC, 2nd Floor, B229 3900 Woodland Ave., Philadelphia, PA 19104, USA. Electronic address: gehrman@upenn.edu.

Abstract

Insomnia affects up to 15% of the US population. There are effective pharmacologic and behavioral treatments for insomnia; however, there is often no one-size-fits-all intervention. This article discusses the leading behavioral treatment of insomnia, cognitive behavioral therapy for insomnia, and its ability to be tailored to an individual's specific symptoms. It then discusses pharmacologic options for treating insomnia, and offers some guidance on medication selection to enhance personalized care. In addition, it discusses how the current evidence base can help providers make choices between pharmacologic and behavioral treatments.