Nanoparticles promote functional healing following
spinal cord injury
Paralyzing damage in spinal cord injury (SCI) is often caused by the zealous immune response to the injury. NIBIB-funded engineers have developed nanoparticles that lure immune cells away from the spinal cord, allowing regeneration that restored spinal cord function in mice.
The team tested the nanoparticles in a mouse SCI model, where they observed reduced fibrosis and increased regenerative processes. In addition, in functional studies, mice that received the nanoparticle therapy showed enhanced locomotor function.