CIENCIASMEDICASNEWS: Medical News | Medical Articles: Enhancing the maturation of sensory neurons in-vitro

martes, 30 de julio de 2019

Medical News | Medical Articles: Enhancing the maturation of sensory neurons in-vitro

	July 30, 2019
	Cell Biology
	The latest cell & molecular biology news from News Medical

Enhancing the maturation of sensory neurons in-vitro

Used in conjunction with sensory neuron maintenance medium the Maturation Maximizer from Axol Bioscience, will significantly reduce the time to maturation of sensory neurons by over 40 days and increases key marker expression by on average 30-45%, enhancing the maturation of sensory neurons in-vitro.

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Single Cell RNA-Seq

Single Cell RNA-Seq is a tool which enables researchers to study thousands of single cell transcriptomes, thus ensuring an immensely wide range of study into tissues available at the level of single cells. This kind of data is crucial to the right understanding of a host of diseases and immune processes.

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Flexible Methods for Long-Read RNA Sequencing

RNA analysis has become a vital tool for researchers looking for insight into the study of living things, revealing details about the dynamics of the transcriptome, from single cells to whole tissues.

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	Stem Cell Sources, Types, and Uses in Research Stem cells are undifferentiated cells that are capable of self-renewal or differentiation into a specialized cell. They exist within areas of the body known as biological niches and are essential for growth during childhood, and homeostasis throughout adulthood. Thus, understanding the biological processes that underpin these cells can have invaluable implications for regenerative medicine, disease treatment, and injury recovery.

	Study sheds light on complex caspase-1-induced cell death mechanisms Most unnecessary or dangerous cells such as virus-infected cells commit suicide by activating an in-built suicide program. This type of cell death is referred to as "programmed cell death". Until about year 2000, it was considered that apoptosis is almost the sole mode of programmed cell death at least in mammals.

	New study reveals 'clutch' proteins responsible for putting T cell activation 'into gear' In collaborative research, scientists from three continents were able to discover a crucial bit of information about how T cells move proteins inside them to drive the immune response. This could help evolve specific new treatments centered on T cell selectivity.

	Applying Ultrasound to Cell Sorting A team from the University of Toronto have pioneered a new of rapidly sizing and counting cells. Strohm et al. combined a microfluidics-based single-cell stream with ultrasound acoustics to yield measurable ultrasound echoes of single cells.

	Nanoparticles used to deliver CRISPR gene editing tools into the cell Researchers from Tufts University and the Chinese Academy of Sciences have developed a novel method to effectively deliver the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeat (CRISPR) associated protein 9) gene editing tools into the liver for genetic studies.

	Alternate cell growth pathway could open door to new treatments for metastatic cancers While researchers have a basic understanding of how primary cancer cells grow, less is known about metastasis, the deadly process by which cancers spread. A team led by Dr. Paul Krebsbach, dean of UCLA's School of Dentistry and professor of periodontics, has found that mEAK-7, a gene they discovered last year, may play a significant role in cancer metastasis, at least in lung cancers.

	Mathematical model helps quantify metastatic cell behavior Cancer metastasis is a difficult stage to battle, especially if cancer cells are proliferating at a rapid pace. A new study reveals that metastatic cells change their shape to spread to other parts of the body. Researchers formulated a mathematical model to study metastatic cell behavior and similar cellular systems.