Loss of USP18 in microglia induces white matter pathology | Acta Neuropathologica Communications | Full Text

Loss of USP18 in microglia induces white matter pathology | Acta Neuropathologica Communications | Full Text

Acta Neuropathologica Communications

Loss of USP18 in microglia induces white matter pathology

• Marius Schwabenland,
• Omar Mossad,
• Adam G. Peres,
• Franziska Kessler,
• Feres Jose Mocayar Maron,
• Laura-Adela Harsan,
• Thomas Bienert,
• Dominik von Elverfeldt,
• Klaus-Peter Knobeloch,
• Ori Staszewski,
• Frank L. Heppner,
• Marije E. C. Meuwissen,
• Grazia M. S. Mancini,
• Marco Prinz and
• Thomas BlankEmail authorView ORCID ID profile

Acta Neuropathologica Communications20197:106

https://doi.org/10.1186/s40478-019-0757-8

©  The Author(s). 2019

• Received: 16 May 2019
• Accepted: 20 June 2019
• Published: 4 July 2019

Keywords

• Microglia
• Type I interferon
• Usp18
• White matter
• Phagocytosis
• Corpus callosum
• Behavior
• Magnet resonance spectroscopy
• Microgliosis