CIENCIASMEDICASNEWS: Medical News | Medical Articles: Breakthrough antibody treatment suppresses HIV without antivirals

jueves, 9 de mayo de 2019

Medical News | Medical Articles: Breakthrough antibody treatment suppresses HIV without antivirals

	May 9, 2019
	Antibodies
	The latest antibodies news from News Medical

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			Breakthrough antibody treatment suppresses HIV without antivirals Research published yesterday in The New England Journal of Medicine describes how an antibody that prevents HIV binding to human immune cells was shown to be able to suppress levels of HIV for up to four months.

			Storing and Handling Antibodies for Research Antibodies are proteins produced by the immune system as part of the body's defense against pathogens. Each antibody is specific to one molecule or a small number of molecules, known as antigens. Antibodies are commonly used in research to understand disease processes. However, care must be taken when handling and storing these proteins

	Unusually small antibodies could help CAR T-cell therapies to kill solid tumors In 1989, two undergraduate students at the Free University of Brussels were asked to test frozen blood serum from camels, and stumbled on a previously unknown kind of antibody. It was a miniaturized version of a human antibody, made up only of two heavy protein chains, rather than two light and two heavy chains. As they eventually reported, the antibodies' presence was confirmed not only in camels, but also in llamas and alpacas.

	Researchers succeed in humanization of mouse antibodies targeting human herpesvirus 6B A research group led by Professor Yasuko Mori (Division of Clinical Virology, Center for Infectious Diseases, Kobe University) have succeeded in humanization of mouse antibodies that can neutralize the infection caused by human herpesvirus 6B.

	New sepsis detector uses photonics to make accurate diagnosis in less than thirty minutes European scientists have developed a new sepsis detector that uses photonics to produce a while-you-wait diagnosis, from sample to result, in less than thirty minutes. Programmed to detect proteins and E.coli, one of the deadly bacteria that can cause the human body to go into septic shock, the detector then uses light to look for specific biomarkers (the tell-tale signs or an indicator of a disease) that are as small as few nanometers in size, or 1 / 1,000,000th of the thickness of a single human hair.

	TET proteins help regulate gene activity vital for normal antibody production A family of cancer suppressive proteins, known as TET proteins, help regulate gene activity via their influence on chromosomal architecture. However, until now it wasn't entirely clear how genes were activated by TET proteins to make sure that cells perform their normal functions efficiently.

	Study identifies antigens targeted by antibody response to Kawasaki Disease A new study identifies antigens targeted by the antibody response of children with Kawasaki Disease (KD). Findings will be presented during the Pediatric Academic Societies (PAS) 2019 Meeting, taking place on April 24 - May 1 in Baltimore.