CIENCIASMEDICASNEWS: Medical News | Medical Articles: DNA Damage Repair and the Progression of the Cell Cycle

miércoles, 8 de mayo de 2019

Medical News | Medical Articles: DNA Damage Repair and the Progression of the Cell Cycle

	May 8, 2019
	Genetics
	The latest Genetics news from News Medical

DNA Damage Repair and the Progression of the Cell Cycle

All stages of the cell cycle in normal cells are tightly controlled. In cancer cells, several proteins and genes that impact the progression of the cell cycle are overexpressed or mutated and turn into oncogenes. The proteins involved in cell cycle regulation, specifically DNA damage and DNA replication, are significant cancer therapeutic targets.

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			New study describes process to diagnose rare genetic diseases in record time Researchers at Rady Children's Institute for Genomic Medicine and its partners, including Fabric Genomics, have today published in Science Translational Medicine a new study documenting the process to diagnose rare genetic diseases in record time.

			New genetic test identifies many disease-causing gene variations in high-risk populations Researchers at Nemours Children's Health System have developed a new low-cost genetic test that accurately identified more than 200 known disease-causing gene variations in two high-risk populations, the Old Order Amish and Old Order Mennonites of Lancaster County, Pennsylvania.

	Study examines differences in genetic risk factors for childhood-onset and adult-onset asthma Asthma, a common respiratory disease that causes wheezing, coughing and shortness of breath, is the most prevalent chronic respiratory disease worldwide. A new study, published April 30, 2019 in Lancet Respiratory Medicine, is the first large investigation to examine the differences in genetic risk factors for childhood-onset and adult-onset asthma.

	First GWAS for Type 2 diabetes in youth reveals seven genetic variants associated with the disease Pediatric diabetes and genetic researchers with the First Genome-Wide Association Study (GWAS) for Type 2 diabetes in youth said they discovered seven genetic variants associated with the disease in young people.

	Combination of biological markers and genetic changes can predict radiation sensitivity Latest results from a project to discover what makes a cancer patient more likely to suffer adverse side-effects after radiotherapy have shown that a combination of biological markers and certain genetic changes can predict radiation sensitivity.

	Mount Sinai study identifies 20 new genetic associations with bipolar disorder In the largest study of its kind, involving more than 50,000 subjects in 14 countries, researchers at the Icahn School of Medicine at Mount Sinai and more than 200 collaborating institutions have identified 20 new genetic associations with one of the most prevalent and elusive mental illnesses of our time--bipolar disorder.

	Genetic test for low birth weight on the horizon Researchers have successfully identified 190 genetic factors associated with a low birth weight. They hope that this may one day be used to develop a universal genetic test.