Updated National Comprehensive Cancer Network (NCCN) Genetic/Familial High-Risk Assessment: Breast and Ovarian and NCCN Genetic/Familial High-Risk Assessment: Colorectal as references 12 and 13, respectively.
Added text to state that a systematic review identified 13 published studies that used a randomized controlled trial design to compare pretest and posttest outcomes for in-person genetic counseling with telephone counseling. Knowledge and psychosocial outcomes were found to be noninferior, equivalent, or not statistically significant between telephone counseling and in-person counseling.
Added text to state that a group reported results of a study where all participants received in-person pretest counseling at one of five participating sites. Those participants willing to be randomized had their results disclosed by telephone or in person. Notably, 30% of participants in this study had multigene panel testing. In this trial, telephone disclosure was noninferior to in-person results disclosure when comparing primary psychosocial outcomes (cited Bradbury et al. as reference 46).
Updated NCCN Genetic/Familial High-Risk Assessment: Breast and Ovarian as reference 43.
Revised text to state that clinical confirmation of health-related positive results from direct-to-consumer testing entails repeating the test in a Clinical Laboratory Improvement Act–certified lab, as well as individual review and verification of the result by laboratory personnel.
ver historia personal en: www.cerasale.com.ar [dado de baja por la Cancillería Argentina por temas políticos, propio de la censura que rige en nuestro medio]//
weblog.maimonides.edu/farmacia/archives/UM_Informe_Autoevaluacion_FyB.pdf - //
weblog.maimonides.edu/farmacia/archives/0216_Admin_FarmEcon.pdf - //
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