domingo, 16 de abril de 2017

Next Generation Sequencing and Multi-Gene Panel Testing: Implications for the Oncology Nurse. - PubMed - NCBI

Next Generation Sequencing and Multi-Gene Panel Testing: Implications for the Oncology Nurse. - PubMed - NCBI





 2017 Apr 5. pii: S0749-2081(17)30017-7. doi: 10.1016/j.soncn.2017.02.007. [Epub ahead of print]

Next Generation Sequencing and Multi-Gene Panel Testing: Implications for the Oncology Nurse.

Abstract

OBJECTIVES:

To review past, current, and future events in genetics and discuss how genetic testing information personalizes cancer screening, detection, and treatment. A case study is presented to illustrate key points.

DATA SOURCES:

National guidelines, evidence-based summaries, peer-reviewed studies, editorials, and web sites.

CONCLUSION:

Multi-gene testing using next-generation sequencing has changed the landscape for hereditary cancer syndromes.

IMPLICATIONS FOR NURSING PRACTICE:

Nurses have key roles in personalizing health care including recognizing the complexities of genetic testing, assessing family history, understanding gene/environment factors, referring for genetics consultations, and promoting registry studies. In order to be effective, nurses must stay current with the rapidly-changing technology and guidelines for genetic evaluations and testing.

KEYWORDS:

ATM gene; genetic testing; hereditary breast cancer; multi-gene panels; next-generation sequencing; personalized health care

PMID:
 
28390840
 
DOI:
 
10.1016/j.soncn.2017.02.007

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