lunes, 17 de abril de 2017

Childhood Brain Stem Glioma Treatment (PDQ®)—Health Professional Version - National Cancer Institute

Childhood Brain Stem Glioma Treatment (PDQ®)—Health Professional Version - National Cancer Institute

National Cancer Institute

Childhood Brain Stem Glioma Treatment (PDQ®)–Health Professional Version



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Changes to This Summary (04/14/2017)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.
Added Puget et al. as reference 9.
Revised text to state that diffuse intrinsic pontine gliomas (DIPGs) are also generally anaplastic astrocytoma (World Health Organization [WHO] grade 3) or glioblastoma (WHO grade 4) by morphological criteria, although WHO grade 2 regions can also be identified (cited Hoffman et al. as reference 15).
This section was extensively revised.
Revised text to state that progression of a DIPG is anticipated generally within 1 year of completing radiation therapy. Also revised text to state that patients or families who desire additional disease-directed therapy should consider entering trials of novel therapeutic approaches because no standard agents have demonstrated clinically significant activity.
Added text to state that regardless of whether a decision is made to pursue disease-directed therapy at the time of progression, palliative care remains a central focus of management. This ensures that quality of life is maximized while attempting to reduce symptoms and stress related to the terminal illness.
Added Huynh-Le et al. as reference 2.
This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.
  • Updated: April 14, 2017

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