Coronaviruses: emerging and re-emerging pathogens in humans and animals
Edited by Susanna K. P. Lau
Some of the coronavirus infections raise very serious problems in the past 2 decades, such as the severe acute respiratory syndrome (SARS) outbreak in 2003, and porcine epidemic diarrhea virus (PEDV) which has caused millions of deaths in piglets worldwide. More recently, we are threatened by the outbreak of Middle East respiratory syndrome (MERS) which has spread to various countries including South Korea.
This thematic series published in Virology Journal emphasizes advances and key discoveries in the animal origin, viral evolution, epidemiology, diagnostics and pathogenesis of different emerging and re-emerging coronaviruses.
Listen to our podcast on coronaviruses by Editor-in-Chief, Linfa Wang!
- RESEARCH
Occurrence and sequence analysis of porcine deltacoronaviruses in southern China
Following the initial isolation of porcine deltacoronavirus (PDCoV) from pigs with diarrheal disease in the United States in 2014, the virus has been detected on swine farms in some provinces of China. To date...Virology Journal 2016 13:136Published on: 5 August 2016 - SHORT REPORT
Alphacoronavirus in urban Molossidae and Phyllostomidae bats, Brazil
Bats have been implicated as the main reservoir of coronavirus (CoV). Thus the role of these hosts on the evolution and spread of CoVs currently deserve the attention of emerging diseases surveillance programs...Virology Journal 2016 13:110Published on: 24 June 2016 - RESEARCH
Bovine coronavirus in naturally and experimentally exposed calves; viral shedding and the potential for transmission
Bovine coronavirus (BCoV) is a widely distributed pathogen, causing disease and economic losses in the cattle industry worldwide. Prevention of virus spread is impeded by a lack of basic knowledge concerning v...Virology Journal 2016 13:100Published on: 13 June 2016 - REVIEW
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir
Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) is a novel coronavirus discovered in 2012 and is responsible for acute respiratory syndrome in humans. Though not confirmed yet, multiple surveillance an...Virology Journal 2016 13:87Published on: 3 June 2016 - RESEARCH
S1 domain of the porcine epidemic diarrhea virus spike protein as a vaccine antigen
Porcine epidemic diarrhea virus (PEDV) is a highly contagious virus infecting pigs of all ages with high morbidity and mortality among newborn piglets. Currently, there is no effective vaccine available to pro...Virology Journal 2016 13:57Published on: 1 April 2016 - RESEARCH
Characterization and analysis of an infectious bronchitis virus strain isolated from southern China in 2013
Infectious bronchitis is a severe disease caused by infectious bronchitis virus (IBV) that affects fowl flocks worldwide. The understanding of the mechanisms involved in IBV evolution and variation would provi...Virology Journal 2016 13:40Published on: 9 March 2016 - RESEARCH
Molecular epidemiology and evolutionary histories of human coronavirus OC43 and HKU1 among patients with upper respiratory tract infections in Kuala Lumpur, Malaysia
Despite the worldwide circulation of human coronavirus OC43 (HCoV-OC43) and HKU1 (HCoV-HKU1), data on their molecular epidemiology and evolutionary dynamics in the tropical Southeast Asia region is lacking.Virology Journal 2016 13:33Published on: 25 February 2016 - REVIEW
Coronaviruses and the human airway: a universal system for virus-host interaction studies
Human coronaviruses (HCoVs) are large RNA viruses that infect the human respiratory tract. The emergence of both Severe Acute Respiratory Syndrome and Middle East Respiratory syndrome CoVs as well as the yearl...Virology Journal 2016 13:24Published on: 6 February 2016 - ERRATUMVirology Journal 2016 13:19Published on: 1 February 2016
- RESEARCH
Molecular characterization of human coronaviruses and their circulation dynamics in Kenya, 2009–2012
Human Coronaviruses (HCoV) are a common cause of respiratory illnesses and are responsible for considerable morbidity and hospitalization across all age groups especially in individuals with compromised immuni...Virology Journal 2016 13:18Published on: 1 February 2016 - EDITORIAL
Coronaviruses: emerging and re-emerging pathogens in humans and animals
The severe acute respiratory syndrome coronavirus (SARS-CoV) and recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV) epidemics have proven the ability of coronaviruses to cross species bar...Virology Journal 2015 12:209Published on: 22 December 2015 - REVIEW
Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesis
Middle-East Respiratory Syndrome coronavirus (MERS-CoV) was identified to cause severe respiratory infection in humans since 2012. The continuing MERS epidemic with a case-fatality of more than 30 % poses a ma...Virology Journal 2015 12:218Published on: 22 December 2015 - REVIEW
MERS coronavirus: diagnostics, epidemiology and transmission
The first known cases of Middle East respiratory syndrome (MERS), associated with infection by a novel coronavirus (CoV), occurred in 2012 in Jordan but were reported retrospectively. The case first to be publ...Virology Journal 2015 12:222Published on: 22 December 2015 - REVIEW
Bat origin of human coronaviruses
Bats have been recognized as the natural reservoirs of a large variety of viruses. Special attention has been paid to bat coronaviruses as the two emerging coronaviruses which have caused unexpected human dise...Virology Journal 2015 12:221Published on: 22 December 2015 - REVIEW
Porcine epidemic diarrhea virus: An emerging and re-emerging epizootic swine virus
The enteric disease of swine recognized in the early 1970s in Europe was initially described as “epidemic viral diarrhea” and is now termed “porcine epidemic diarrhea (PED)”. The coronavirus referred to as PED...Virology Journal 2015 12:193Published on: 22 December 2015
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