Sociodemographic, psychosocial and clinical factors associated with uptake of genetic counseling for hereditary cancer: a systematic review. - PubMed - NCBI

Sociodemographic, psychosocial and clinical factors associated with uptake of genetic counseling for hereditary cancer: a systematic review. - PubMed - NCBI

Clin Genet. 2016 Sep 19. doi: 10.1111/cge.12868. [Epub ahead of print]

Sociodemographic, psychosocial and clinical factors associated with uptake of genetic counseling for hereditary cancer: a systematic review.

Willis AM1, Smith SK2, Meiser B2, Ballinger ML3, Thomas DM3, Young MA4.

Author information

Abstract

Evidence suggests that a significant proportion of individuals referred to cancer genetic counselling (GC) do not attend, and thus may not be engaged in adequate cancer risk management. We aimed to review the literature to better understand barriers to accessing GC and how they may be overcome. We conducted a systematic literature search for articles examining factors influencing cancer GC uptake as well as motivators and barriers to GC attendance. Factors were categorised as sociodemographic, psychosocial or clinical. The literature search identified 1,413 citations, 35 of which met the inclusion criteria. GC uptake ranged from 19% to 88%. With the exceptions of education level, socioeconomic status, cancer-specific distress, personal cancer diagnosis and actual and perceived risk of cancer, support was lacking for most sociodemographic, clinical and psychosocial factors as predictors of GC uptake. Cost and logistical barriers, emotional concerns, family concerns and low perceived personal relevance were reported as important considerations for those declining GC. We conclude that there is poor understanding of GC and a lack of decision support among those referred to GC. Research into ways of providing education and support to referred individuals will be important as the scope and availability of genetic counselling and testing broaden.

This article is protected by copyright. All rights reserved.

KEYWORDS:

Barriers; Genetic counselling; Hereditary cancer; Systematic review; Uptake

PMID:

 

27643459

 

DOI:

 

10.1111/cge.12868

[PubMed - as supplied by publisher]

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GENETIC COUNSELING

Last Updated: Sep 28, 2016

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Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
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