PMKB: Precision Medicine Knowledgebase

PMKB

Welcome to the Precision Medicine Knowledgebase!

The Precision Medicine Knowledgebase (PMKB) is a project of the Institute of Precision Medicine (IPM) at Weill Cornell Medicine.

PMKB is organized to provide information about clinical cancer variants and interpretations in a structured way, as well as allowing users to submit and edit existing entries for continued growth of the knowledgebase. All changes are reviewed by cancer pathologists.

Public Health Genomics Knowledge Base (v1.2)

 Precision Medicine expanded expanded

The Precision Medicine Knowledge Base
Weil Cornell, October 2016

Precision engagement: the PMI’s success will depend on more than genomes and big data
JK Wagner et al, Genetics in Medicine, October 27, 2016

Precision medicine in cardiology.
Antman Elliott M et al. Nature reviews. Cardiology 2016 Oct (10) 591-602

More information on this topic

Last Updated: Oct 27, 2016

• Precision engagement: the PMI’s success will depend on more than genomes and big data
  JK Wagner et al, Genetics in Medicine, October 27, 2016
• The Precision Medicine Knowledge Base
  Weil Cornell, October 2016
• Chemotherapy decisions and patient experience with the recurrence score assay for early-stage breast cancer.
  Friese Christopher R et al. Cancer 2016 Oct
• Clinical Utility of Circulating Tumor DNA for Molecular Assessment and Precision Medicine in Pancreatic Cancer.
  Takai Erina et al. Advances in experimental medicine and biology 2016 92413-17
• Genetics of Sickle Cell-Associated Cardiovascular Disease: An Expert Review with Lessons Learned in Africa.
  Geard Amy et al. Omics : a journal of integrative biology 2016 Oct 20(10) 581-592
• Implementation of Pharmacogenetic Testing Within the Veterans Health Administration From 2011 to 2013.
  Lynch Julie et al. Military medicine 2016 Oct 181(10) 1375-1381
• Integrating precision cancer medicine into healthcare-policy, practice, and research challenges.
  Bertier Gabrielle et al. Genome medicine 2016 Oct 8(1) 108
• Precision medicine in cardiology.
  Antman Elliott M et al. Nature reviews. Cardiology 2016 Oct 13(10) 591-602
• Precision Medicine: the Promise, the Journey, the Future 
  E Lander, Public Health Grand Rounds, Aspen Institute video, October 2016t
• USE OF GENOME DATA IN NEWBORNS AS A STARTING POINT FOR LIFE-LONG PRECISION MEDICINE.
  Brenner Steven E et al. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2016 21568-75
• Delivering on the promise of precision cancer medicine
  MF Berger et al, Genome Medicine, October 25, 2016
• Integrating precision cancer medicine into healthcare—policy, practice, and research challenges
  G Bertier et al, Genome Medicine, October 24, 2016
• Precision Medicine: the Promise, the Journey, the Future 
  E Lander, Public Health Grand Rounds, Aspen Institute video, October 2016t
• A Precision Medicine Approach to Clinical Trials
  R Rubin, JAMA< October 19, 2016
• Advanced Big Data Analytics for -Omic Data and Electronic Health Records: Toward Precision Medicine.
  Wu Po-Yen et al. IEEE transactions on bio-medical engineering 2016 Oct

• CDC Information (18)
• CDC-Authored Pub (8)

• Human (274)
• Pathogen (0)

• Human (26)
• Pathogen (0)

• Human (46)
• Pathogen (1)

• Guidelines (3)
• Tier Table (0)
• Synthesis (4)

• Huamn (1)
• Pathogen (0)

Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB