Gastroenteritis Outbreaks Caused by Norovirus GII.17, Guangdong Province, China, 2014–2015 - Volume 21, Number 7—July 2015 - Emerging Infectious Disease journal - CDC
Volume 21, Number 7—July 2015
Gastroenteritis Outbreaks Caused by Norovirus GII.17, Guangdong Province, China, 2014–2015
Norovirus infection is a leading cause of nonbacterial gastroenteritis outbreaks in industrialized and developing countries (1,2). On the basis of amino acid identity in viral protein 1, noroviruses can be divided into at least 6 genogroups (GI–GVI). GI and GII infect humans and can be further classified into genotypes; at least 9 genotypes belong to GI and 22 belong to GII (3). During the past decade, most reported norovirus outbreaks were caused by GII.4 norovirus (4,5). New variants of GII.4 have emerged approximately every 2–3 years and have caused norovirus gastroenteritis pandemics globally (6). Since 1999, the major circulating genotype in mainland China has been GII.4, accounting for 64% of all genotypes detected (7). In winter 2014–15, norovirus outbreaks in Guangdong Province, China, increased. Sequence analyses showed that the major cause of continuous gastroenteritis outbreaks in the region was a rarely reported norovirus genotype: GII.17.
Dr. Lu is a virologist at the Guangdong Provincial Institution of Public Health, Guangdong Provincial Center for Disease Control and Prevention. His research interest is enteric viruses.
We gratefully acknowledge the efforts of local Centers for Disease Control and Prevention in China in the investigation and reporting of these outbreaks.
This work was supported by 12th Five-Year-Major-projects of the China Ministry of Public Health. Grant no. 2012zx10004-213.
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Suggested citation for this article: Lu J, Sun L, Fang L, Yang F, Mo Y, Lao J, et al. Gastroenteritis outbreaks caused by norovirus GII.17, Guangdong Province, China, 2014–2015. Emerg Infect Dis. 2015 Jul [date cited]. http://dx.doi.org/10.3201/eid2107.150226
1These authors contributed equally to this article.