miércoles, 17 de junio de 2015

Gastroenteritis Outbreaks Caused by Norovirus GII.17, Guangdong Province, China, 2014–2015 - Volume 21, Number 7—July 2015 - Emerging Infectious Disease journal - CDC

full-text ►

Gastroenteritis Outbreaks Caused by Norovirus GII.17, Guangdong Province, China, 2014–2015 - Volume 21, Number 7—July 2015 - Emerging Infectious Disease journal - CDC



Volume 21, Number 7—July 2015

Dispatch

Gastroenteritis Outbreaks Caused by Norovirus GII.17, Guangdong Province, China, 2014–2015

Jing Lu1, Limei Sun1, Lin Fang, Feng Yang, Yanling Mo, Jiaqian Lao, Huanying Zheng, Xiaohua Tan, Hualiang Lin, Shannon Rutherford, Lili Guo, Changwen Ke, and Li HuiComments to Author 
Author affiliations: Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China (J. Lu, L. Sun, L. Fang, F. Yang, Y. Mo, J. Lao, H. Zheng, X. Tan, H. Lin, L. Guo, C. Ke, L. Hui)Guangdong Provincial Institution of Public Health, Guangzhou (J. Lu, H. Lin)Centre for Environment and Population Health, Brisbane, Queensland, Australia (S. Rutherford)

Abstract

In the past decade, the most prevalent norovirus genotype causing viral gastroenteritis outbreaks worldwide, including China, has been GII.4. In winter 2014–15, norovirus outbreaks in Guangdong, China, increased. Sequence analysis indicated that 82% of the outbreaks were caused by a norovirus GII.17 variant.
Norovirus infection is a leading cause of nonbacterial gastroenteritis outbreaks in industrialized and developing countries (1,2). On the basis of amino acid identity in viral protein 1, noroviruses can be divided into at least 6 genogroups (GI–GVI). GI and GII infect humans and can be further classified into genotypes; at least 9 genotypes belong to GI and 22 belong to GII (3). During the past decade, most reported norovirus outbreaks were caused by GII.4 norovirus (4,5). New variants of GII.4 have emerged approximately every 2–3 years and have caused norovirus gastroenteritis pandemics globally (6). Since 1999, the major circulating genotype in mainland China has been GII.4, accounting for 64% of all genotypes detected (7). In winter 2014–15, norovirus outbreaks in Guangdong Province, China, increased. Sequence analyses showed that the major cause of continuous gastroenteritis outbreaks in the region was a rarely reported norovirus genotype: GII.17.
Dr. Lu is a virologist at the Guangdong Provincial Institution of Public Health, Guangdong Provincial Center for Disease Control and Prevention. His research interest is enteric viruses.

Acknowledgments

We gratefully acknowledge the efforts of local Centers for Disease Control and Prevention in China in the investigation and reporting of these outbreaks.
This work was supported by 12th Five-Year-Major-projects of the China Ministry of Public Health. Grant no. 2012zx10004-213.

References

  1. Patel MMWiddowson MAGlass RIAkazawa KVinje JParashar UDSystematic literature review of role of noroviruses in sporadic gastroenteritis.Emerg Infect Dis2008;14:122431DOIPubMed
  2. Payne DCVinje JSzilagyi PGEdwards KMStaat MAWeinberg GANorovirus and medically attended gastroenteritis in U.S. children. N Engl J Med2013;368:112130DOIPubMed
  3. Kroneman AVega EVennema HVinje JWhite PAHansman GProposal for a unified norovirus nomenclature and genotyping. Arch Virol.2013;158:205968 . DOIPubMed
  4. Centers for Disease Control and PreventionEmergence of new norovirus strain GII.4 Sydney–United States, 2012. MMWR Morb Mortal Wkly Rep.2013;62:55 .PubMed
  5. van Beek JAmbert-Balay KBotteldoorn NEden JSFonager JHewitt JIndications for worldwide increased norovirus activity associated with emergence of a new variant of genotype II.4, late 2012. [PMID]Euro Surveill2013;18:89.PubMed
  6. Bok KAbente EJRealpe-Quintero MMitra TSosnovtsev SVKapikian AZEvolutionary dynamics of GII.4 noroviruses over a 34-year period. J Virol2009;83:11890901DOIPubMed
  7. Yu YYan SLi BPan YWang Y. Genetic diversity and distribution of human norovirus in China (1999–2011). Biomed Res Int. 2014;2014:196169.PMID: 24672783DOI
  8. Kojima SKageyama TFukushi SHoshino FBShinohara MUchida KGenogroup-specific PCR primers for detection of Norwalk-like viruses. J Virol Methods2002;100:10714DOIPubMed
  9. Vega EBarclay LGregoricus NShirley SHLee DVinje JGenotypic and epidemiologic trends of norovirus outbreaks in the United States, 2009 to 2013. J Clin Microbiol2014;52:14755DOIPubMed
  10. Shen ZQian FLi YHu YYuan ZZhang JNovel norovirus GII.4 variant, Shanghai, China, 2012. Emerg Infect Dis2013;19:13379.DOIPubMed
  11. Kiulia NMMans JMwenda JMTaylor MB. Norovirus GII.17 predominates in selected surface water sources in Kenya. Food Environ Virol.2014;6:221–31.
  12. Centers for Disease Control and PreventionUpdated norovirus outbreak management and disease prevention guidelines. MMWR Recomm Rep.2011;60(RR-3):118 .PubMed
  13. Papaventsis DCDove WCunliffe NANakagomi OCombe PGrosjean PNorovirus infection in children with acute gastroenteritis, Madagascar, 2004–2005. Emerg Infect Dis2007;13:90811DOIPubMed

Figures

Technical Appendix

Suggested citation for this article: Lu J, Sun L, Fang L, Yang F, Mo Y, Lao J, et al. Gastroenteritis outbreaks caused by norovirus GII.17, Guangdong Province, China, 2014–2015. Emerg Infect Dis. 2015 Jul [date cited]. http://dx.doi.org/10.3201/eid2107.150226
DOI: 10.3201/eid2107.150226
1These authors contributed equally to this article.

No hay comentarios:

Publicar un comentario