CDC Podcast on Familial HypercholesterolemiaOn September 20th, 2010, CDC’s Office of Public Health Genomics (OPHG) released a podcast about the benefits of cascade screening to identify familial hypercholesterolemia, a common genetic disorder that causes high levels of low-density lipoprotein (or LDL) cholesterol that are present from birth. In the podcast, Renée M. Ned, PhD, MMSc, health scientist from OPHG, explains that:
- early detection and treatment of familial hypercholesterolemia has tremendous potential to prevent the onset of, and death related to, coronary heart disease;
- physicians should encourage patients to document their family health history, and make sure to collect and continually monitor this information;
- once a patient with FH is identified, physicians should use cascade testing to enable the early detection and treatment of affected relatives.
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Read the transcript.
Web ResourcesNational Institute for Health and Clinical Excellence (NICE). Identification and management of familial hypercholesterolaemia. NICE clinical guideline CG71. Issued August 2008.
- Familial hypercholesterolaemia (CG71)
- Make Early Diagnosis to Prevent Early Death (MEDPED)
- Online Mendelian Inheritance in Man (OMIM)-- Hypercholesterolemia, Autosomal Dominant
- World Health Organization (WHO). 1999. Familial Hypercholesterolaemia (FH): Report of a second WHO Consultation. Geneva. [PDF 2.45 MB]