Short RNAs may prevent neuron death linked to ALS, dementia

Short RNAs may prevent neuron death linked to ALS, dementia At a Glance In cell and animal models, short RNA molecules stopped or reversed abnormal clumping of the TDP-43 protein, which is linked to brain cell death. The results suggest RNA-based therapies could one day be used to treat diseases marked by abnormal TDP-43, including ALS and Alzheimer’s disease. https://www.nih.gov/news-events/nih-research-matters/short-rnas-may-prevent-neuron-death-linked-als-dementia