MRI Predicts Survival Better Than Histopathology in Rectal Cancer Edited by Mamta Pawara ++++

https://www.medscape.com/viewarticle/mri-predicts-survival-better-than-histopathology-rectal-2026a1000kgu MRI-detected extramural venous invasion (mrEMVI) in patients with rectal cancer was associated with a more than fivefold increased risk for recurrence and a more than threefold increased risk for death; however, postoperative histopathologically detected EMVI (pEMVI) showed no significant prognostic value in a prospective single-centre cohort. The HPV Vaccine at 20: Progress Made, Challenges Ahead Cristina Ferrario https://www.medscape.com/viewarticle/hpv-vaccine-20-progress-made-challenges-ahead-2026a1000ksf June 19, 2026 Twenty years ago, a major milestone in cancer prevention was reached when the US. The FDA approved the first human papillomavirus (HPV) vaccine. Introduced in 2006, the quadrivalent vaccine protected against HPV types 16 and 18, which are responsible for most HPV-related cancers, as well as HPV types 6 and 11, which cause genital warts but have low oncogenic potential. Patients With Breast Cancer Taking GLP-1s Had Better Survival Sharon Worcester https://www.medscape.com/viewarticle/patients-breast-cancer-taking-glp-1s-had-better-survival-2026a1000kqq June 19, 2026 Once again, a large observational study suggests GLP-1 drugs confer an all-cause mortality benefit among patients with cancer. The study, comparing GLP-1 use vs nonuse in more than 137,000 patients with breast cancer, showed a significant 4% increase in overall survival (OS) in those taking a GLP-1 drug. Nonconventional B-Cell Depletion Strategies Offer Potential Immune Reset in Refractory Autoimmune Disease Manuela Callari https://www.medscape.com/viewarticle/nonconventional-b-cell-depletion-strategies-offer-potential-2026a1000kld LONDON — Complete eradication of pathogenic B cells and plasma cells within deep tissue niches could offer an “immune reset” for patients with highly refractory, severe autoimmune diseases, according to clinical data presented at the European Alliance of Associations for Rheumatology (EULAR) 2026 Annual Meeting.