Swiss centenarians show youthful blood protein profiles in aging study

https://www.news-medical.net/news/20260224/Swiss-centenarians-show-youthful-blood-protein-profiles-in-aging-study.aspx In Switzerland, 0.02% of the population lives beyond the age of 100. Could there be biological characteristics associated with this exceptional longevity? As part of the "SWISS100" study, the first large-scale Swiss research project dedicated to centenarians, a team from the University of Geneva (UNIGE) and the University of Lausanne (UNIL) compared the blood profiles of centenarians with those of octogenarians, and then with those of individuals aged 30 to 60. Across 37 proteins, centenarians show profiles surprisingly close to those of younger individuals, particularly with remarkably low oxidative stress markers. Among the other proteins identified, at least three are involved in the regulation of the extracellular matrix (the "cement" of our body). Others could play a protective role against tumor development or be involved in lipid and glucose metabolism. These findings are published in the journal Aging Cell.