The Lancet's COVID-19 Resource Centre: the first Article to develop and validate classification criteria to define COVID-19-specific hyperinflammation, and more.

 

New COVID-19 Content is Now Available

Dear Victor Norberto,

New this week: Some patients with COVID-19 develop a COVID-19-associated hyperinflammatory syndrome that has similarities with other hyperinflammatory disorders. An Article published in The Lancet Rheumatology is the first to develop and validate classification criteria to define COVID-19-specific hyperinflammation. The authors compared published clinical data for COVID-19 with clinical features of other hyperinflammatory or cytokine storm syndromes. Based on a framework of conserved clinical characteristics, they developed a six-criterion additive scale for COVID-19-specific hyperinflammation syndrome (cHIS score), before validating the association of the cHIS score with in-hospital mortality and need for mechanical ventilation in 299 in-patients with COVID-19. Though independent validation is needed, the authors suggest that the cHIS scale may help define target patient populations for clinical trials and potentially for treatment with immunomodulatory therapies. Read the Article here.

We hope you find the Resource Centre on COVID-19 to be informative. 

Yours sincerely,

The Lancet

NEW content on COVID-19

The Lancet Lockdown impact on COVID-19 epidemics in regions across metropolitan France Confronting antimicrobial resistance beyond the COVID-19 pandemic and the 2020 US election Offline: Science and the breakdown of trust Leveraging the advances in HIV for COVID-19 Building a resilient NHS, for COVID-19 and beyond Minimising long-term effect of COVID-19 in dementia care Remdesivir and COVID-19 Remdesivir and COVID-19 Remdesivir and COVID-19 Remdesivir and COVID-19 Remdesivir and COVID-19 – Authors' reply US election 2020: public health The Lancet Diabetes & Endocrinology Diabetes, like COVID-19, is a wicked problem The Lancet Global Health Sanctions on Syria Open Access Sanctions on Syria Open Access The Lancet HIV Public Health England's political end The Lancet Infectious Diseases The mother of invention Decarceration and community re-entry in the COVID-19 era Low risk of SARS-CoV-2 transmission by fomites in real-life conditions The Lancet Public Health Unemployment and child health during COVID-19 in the USA Open Access Understanding the effects of COVID-19 on health care and systems Open Access The Lancet Respiratory Medicine False-positive COVID-19 results: hidden problems and costs Completion of clinical trials in light of COVID-19 The Lancet Rheumatology Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study Defining the scourge of COVID-19 hyperinflammatory syndrome COVID-19 and African rheumatology: progress in adversity EBioMedicine Differential expression of ACE2 in the respiratory tracts and its relationship to COVID-19 pathogenesis Open Access Characterizing COVID-19 maternal-fetal transmission and placental infection using comprehensive molecular pathology Open Access