New research in has uncovered the mechanisms by which bladder stretch is sensed and the urethral reflexes involved in urination are controlled. The findings pinpoint the gene PIEZO2 as a key mechanosensor for interoception, which is the sensory regulation and awareness of what’s happening inside our bodies. The research, conducted jointly by the National Center for Complementary and Integrative Health, the National Institute of Neurological Disorders and Stroke, and the Scripps Research Institute was published in a recent issue of the journal Nature.
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