SARS-CoV-2 infection analysis could help fight against COVID-19
Researchers in the United States has provided a detailed catalog of the interactions that occur between host cell proteins and RNA and the RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the course of infection.
SARS-CoV-2 is the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic that is increasingly posing a threat to global public health and the worldwide economy.
By integrating the analysis across various time points, species, and other positive single-stranded RNA viruses, the researchers have identified both shared and SARS-CoV-2-specific patterns of RNA–host protein interactions.
The team, from Stanford University and Yale University, says the findings may help to inform future studies aiming to understand viral pathogenesis and potential therapeutic strategies to combating SARS-CoV-2 infection.
A pre-print version of the paper is available in the server bioRxiv*, while the article undergoes peer review.
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