CIENCIASMEDICASNEWS: Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study. Zivanovic Bujak Andjelija et al. PLoS medicine 2020 Oct (10) e1003363

lunes, 12 de octubre de 2020

Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study. Zivanovic Bujak Andjelija et al. PLoS medicine 2020 Oct (10) e1003363

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breast cancer ribbon with DNA and woman on it

Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study.
Zivanovic Bujak Andjelija et al. PLoS medicine 2020 Oct (10) e1003363

We established a prospective ctDNA testing program for patients with mBC to assess the feasibility of this approach to guide patient management. Using a combination of different genomic approaches, actionable alterations were identified in 44% of patients, and clinical management was directly altered by ctDNA testing in 39% of these cases.