Publication Date: Oct 1, 2020
Advanced Molecular Detection Clips Content
NEWS
- The code: How genetic science helped expose a secret coronavirus outbreak
Kaplan S, et al. Washington Post, Sep 24, 2020. - One number could help reveal how infectious a COVID-19 patient is. Should test results include it?
Service RF. Science, Sep 29, 2020. - COVID-19 Genetic Risk Factor Passed Down From Neanderthals, Study Finds
GenomeWeb, Sep 30, 2020.
POLICY
- Genome UK: the future of healthcare -- Strategy setting out the vision to extend the UK�s leadership in genomic healthcare and research.
UK Department of Health and Social Care, Sep 26, 2020.
CONCEPTS / COMMENTS
- Modular synthesis enables molecular ju-jitsu in the fight against antibiotic resistance
Blair DJ, Burke MD. Nature, Sep 23, 2020. - Flawed interferon response spurs severe illness.
Wadman Meredith et al. Science (New York, N.Y.) 2020 09 (6511) 1550-1551 - Rethinking Covid-19 Test Sensitivity - A Strategy for Containment.
Mina Michael J et al. The New England journal of medicine 2020 Sep - Transformative tools for parasitic flatworms.
Anderson Timothy J C et al. Science (New York, N.Y.) 2020 09 (6511) 1562-1564
METHODS / TOOLS
- GeneMates: an R package for detecting horizontal gene co-transfer between bacteria using gene-gene associations controlled for population structure.
Wan Yu et al. BMC genomics 2020 Sep (1) 658 - Universal whole-sequence-based plasmid typing and its utility to prediction of host range and epidemiological surveillance.
Robertson James et al. Microbial genomics 2020 Sep - GraphAligner: rapid and versatile sequence-to-graph alignment.
Rautiainen Mikko et al. Genome biology 2020 Sep (1) 253 - Using affinity propagation clustering for identifying bacterial clades and subclades with whole-genome sequences of Francisella tularensis.
Busch Anne et al. PLoS neglected tropical diseases 2020 Sep (9) e0008018 - Incorporating real-time influenza detection into the test-negative design for estimating influenza vaccine effectiveness: The real-time test-negative design (rtTND).
Feldstein Leora R et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Sep
EVOLUTION / ECOLOGY / POPULATIONS
- Francisella tularensis Subspecies holarctica and Tularemia in Germany.
Appelt Sandra et al. Microorganisms 2020 Sep (9) - Phylogeographical Analysis Reveals the Historic Origin, Emergence, and Evolutionary Dynamics of Methicillin-Resistant Staphylococcus aureus ST228.
Abdelbary Mohamed M H et al. Frontiers in microbiology 2020 2063 - Genomic characterization and phylogenetic evolution of the SARS-CoV-2.
Zhang Rui-Hua et al. Acta virologica 2020 Sep - Genetic Diversity Analysis of Coxsackievirus A8 Circulating in China and Worldwide Reveals a Highly Divergent Genotype.
Song Yang et al. Viruses 2020 Sep (10) - Characterization of Avian Influenza Virus H10-H12 Subtypes Isolated from Wild Birds in Shanghai, China from 2016 to 2019.
Tang Ling et al. Viruses 2020 Sep (10) - Molecular Characterization of Dengue Type 2 Outbreak in Pacific Islands Countries and Territories, 2017-2020.
Inizan Catherine et al. Viruses 2020 Sep (10)
- Expansion of the Emerging Fungal Pathogen Cryptococcus bacillisporus Into America: Linking Phylogenetic Origin, Geographical Spread and Population Under Exposure Risk.
Carvajal Jorge G et al. Frontiers in microbiology 2020 2117 - A metagenomic examination of the pathobiome of the invasive tick species, Haemaphysalis longicornis, collected from a New York City borough, USA.
Tufts Danielle M et al. Ticks and tick-borne diseases 2020 Nov (6) 101516
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
- Plasmid mediated penicillin and tetracycline resistance among Neisseria gonorrhoeae isolates from Kenya.
Kivata Mary Wandia et al. BMC infectious diseases 2020 Sep (1) 703 - Prediction of antimicrobial resistance in clinical Campylobacter jejuni isolates from whole-genome sequencing data.
Dahl Louise Gade et al. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2020 Sep - Paenibacillus infection with frequent viral coinfection contributes to postinfectious hydrocephalus in Ugandan infants
Paulson JN, et al. Sci Transl Med, Sep 30, 2020. - Insertion and deletion evolution reflects antibiotics selection pressure in a Mycobacterium tuberculosis outbreak.
Godfroid Maxime et al. PLoS pathogens 2020 Sep (9) e1008357 - Nanopore MinION Sequencing Reveals Possible Transfer of bla KPC-2 Plasmid Across Bacterial Species in Two Healthcare Facilities.
Prussing Catharine et al. Frontiers in microbiology 2020 2007 - Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni .
Wang Jipeng et al. Science (New York, N.Y.) 2020 09 (6511) 1649-1653
DETECTION / DIAGNOSIS
- Evaluation of a novel multiplex PCR amplicon sequencing assay for detection of human pathogens in Ixodes ticks.
Hojgaard Andrias et al. Ticks and tick-borne diseases 2020 Nov (6) 101504 - Massive and rapid COVID-19 testing is feasible by extraction-free SARS-CoV-2 RT-PCR.
Smyrlaki Ioanna et al. Nature communications 2020 09 (1) 4812 - Mass screening of asymptomatic persons for SARS-CoV-2 using saliva.
Yokota Isao et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020 Sep - Epidemiological Correlates of PCR Cycle Threshold Values in the Detection of SARS-CoV-2. Clinical Infectious Diseases.
Salvatore PP, et al. Clin Infect Dis, Sep 28, 2020. - A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study.
McClain Micah T et al. The Lancet. Infectious diseases 2020 Sep - Laboratory methods supporting measles surveillance in Queensland, Australia, 2010-2017.
McMahon Jamie L et al. Access microbiology 2020 (3) acmi000093 - Epidemiology, clinical pattern and impact of species-specific molecular diagnosis on management of leishmaniasis in Belgium, 2010-2018: A retrospective study.
Vandeputte Martin et al. Travel medicine and infectious disease 2020 Sep 101885
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
- Shiga toxin-producing Escherichia coli O26:H11 associated with a cluster of haemolytic uraemic syndrome cases in South Africa, 2017.
Smith Anthony M et al. Access microbiology 2019 (9) e000061 - Nationwide outbreak of invasive listeriosis associated with consumption of meat products in health care facilities, Germany, 2014-2019.
Lachmann Raskit et al. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2020 Sep - Integrated genomic view of SARS-CoV-2 in India.
Kumar Pramod et al. Wellcome open research 2020 184 - Flight-Associated Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 Corroborated by Whole-Genome Sequencing
Speake H, et al. Emerg Infect Dis, 2020 Dec. - Interregional SARS-CoV-2 spread from a single introduction outbreak in a meat-packing plant in northeast Iowa
Richmond CS, et al. medRxiv, Jun 12, 2020. - First phylogenetic analysis of Malian SARS-CoV-2 sequences provide molecular insights into the genomic diversity of the Sahel region
Kouriba B, et al. medRxiv, Sep 25, 2020. - Molecular epidemiology of HIV-1 in Jiangsu province, Southeast of China: genotypes and HIV-1 transmission networks among newly diagnosed MSM in 2017.
Yin Yueqi et al. AIDS research and human retroviruses 2020 Sep - A heterogenous swine show circuit drives zoonotic transmission of influenza A viruses in the United States
Nelson MI, et al. J Virol. 2020 Sep 30;JVI.01453-20.
ANTIMICROBIALS / VACCINES / INTERVENTIONS
- Safety and Immunogenicity of SARS-CoV-2 MRNA-1273 Vaccine in Older Adults.
Anderson EJ, et al. New Engl J Med, Sep 29, 2020. - Efficacy of an intramuscular bivalent norovirus GI.1/GII.4 virus-like particle vaccine candidate in healthy US adults.
Sherwood James et al. Vaccine 2020 Sep (41) 6442-6449 - Beyond clinical trials: Evolutionary and epidemiological considerations for development of a universal influenza vaccine.
Viboud Cécile et al. PLoS pathogens 2020 Sep (9) e1008583 - Human recombinant soluble ACE2 in severe COVID-19
Zoufaly A, et al. Lancet Respir Med, Sep 24, 2020.
HOST-MICROBE INTERACTIONS
- Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.
Zhang Qian et al. Science (New York, N.Y.) 2020 Sep - Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity
Shrock E, Science, Sep 29, 2020. - The major genetic risk factor for severe COVID-19 is inherited from Neanderthals
Zeberg H, Paabo S. Nature, Sep 30, 2020.
Note:
indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice.Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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