Question Prompt List to Support Patient-Provider Communication in the Use of the 21-Gene Recurrence Test: Feasibility, Acceptability, and Outcomes - PubMed

Question Prompt List to Support Patient-Provider Communication in the Use of the 21-Gene Recurrence Test: Feasibility, Acceptability, and Outcomes - PubMed

Question Prompt List to Support Patient-Provider Communication in the Use of the 21-Gene Recurrence Test: Feasibility, Acceptability, and Outcomes

Jinani Jayasekera 1, Susan T Vadaparampil 2, Susan Eggly 3, Richard L Street Jr 4, Tanina Foster Moore 3, Claudine Isaacs 1, Hyo S Han 2, Bianca Augusto 2, Jennifer Garcia 2, Katherine Lopez 1, Suzanne C O'Neill 1

Affiliations 

• PMID: 32463763
 
• DOI: 10.1200/JOP.19.00661

Abstract

Purpose: The 21-gene recurrence score (RS) assay is used to guide breast cancer treatment decisions but can be poorly understood by patients. We examined the effects of a question prompt list (QPL) on knowledge, distress, and decisional conflict related to genomic testing and treatment in early-stage breast cancer.

Methods: We describe the feasibility and acceptability of the QPL and the impact of the QPL on knowledge, distress, and decisional conflict before and after the receipt of the QPL (MEND 2, N = 65). We also compared distress and decisional conflict between women who received the QPL (MEND 2, N = 65) and a comparable group of women who did not receive the QPL who participated in an earlier observational study within the same clinics (MEND 1, N = 136).

Results: MEND 2 participants indicated high acceptability and feasibility using the QPL. Knowledge increased post-QPL (P < .01) but did not decrease distress. Decisional conflict was lower among women in MEND 2 compared with those in MEND 1 (P < .01), with no statistically significant differences in distress.

Conclusion: The findings suggest that the QPL is feasible, acceptable, can improve knowledge and decrease decisional conflict in the large group of women deciding treatment while integrating RS test results.

Similar articles

• Development and evaluation of an early menopause question prompt list.

  Yeganeh L, Khan NN, Boyle JA, Gibson-Helm M, Teede H, Vincent AJ.Menopause. 2020 Jan;27(1):102-109. doi: 10.1097/GME.0000000000001429.PMID: 31663984
• Development of a question prompt list for women with polycystic ovary syndrome.

  Khan NN, Vincent A, Boyle JA, Burggraf M, Pillay M, Teede H, Gibson-Helm M.Fertil Steril. 2018 Aug;110(3):514-522. doi: 10.1016/j.fertnstert.2018.04.028. Epub 2018 Jun 28.PMID: 29960706
• The evaluation of a question prompt list for attention-deficit/hyperactivity disorder in pediatric care: A pilot study.

  Ahmed R, McCaffery KJ, Silove N, Butow P, Clarke S, Kohn M, Aslani P.Res Social Adm Pharm. 2017 Jan-Feb;13(1):172-186. doi: 10.1016/j.sapharm.2016.01.009. Epub 2016 Mar 3.PMID: 27086063
• The characteristics and effectiveness of Question Prompt List interventions in oncology: a systematic review of the literature.

  Brandes K, Linn AJ, Butow PN, van Weert JC.Psychooncology. 2015 Mar;24(3):245-52. doi: 10.1002/pon.3637. Epub 2014 Jul 31.PMID: 25082386 Review.
• Question Prompt Lists in health consultations: A review.

  Sansoni JE, Grootemaat P, Duncan C.Patient Educ Couns. 2015 Jun 3:S0738-3991(15)00258-X. doi: 10.1016/j.pec.2015.05.015. Online ahead of print.PMID: 26104993 Review.