The Genome Aggregation Database (gnomAD)

The Genome Aggregation Database (gnomAD)



gnomAD includes exomes and genomes from European, Latino African and African American, South Asian, East Asian, Ashkenazi Jewish and other populations.

Deep insight into human genetic variation

A landmark study has identified the genes that it seems people can and cannot live without. The Genome Aggregation Database (gnomAD) has aggregated 15,708 whole genomes and 125,748 exomes (the protein-coding part of the genome), gathered from independent human sequencing studies led by more than 100 investigators. It’s the most comprehensive sets of data and tools for understanding human genetic variation so far — and it’s publicly available.

Nature | 3 min read
Go deeper in with an analysis by genomics researcher Deanna Church in the Nature News & Views article. (7 min read)Reference: 7 papers in Nature, Mature Medicine & Nature Communications