jueves, 7 de mayo de 2020

Profile of a killer: the complex biology powering the coronavirus pandemic

Profile of a killer: the complex biology powering the coronavirus pandemic

A family of killers. Chart showing evolution of SARS-CoV-2.

Profile of a killer

The new coronavirus, SARS-CoV-2, has an array of adaptations that make it much more lethal than the coronaviruses humanity has met so far. Unlike close relatives, SARS-CoV-2 can readily attack human cells at multiple points, with the lungs and the throat being the main targets. Once inside the body, the virus makes use of a diverse arsenal of dangerous molecules. And genetic evidence suggests that it has been hiding in nature possibly for decades. But there are many crucial unknowns about this virus, including how exactly it kills, whether it will evolve into something more — or less — lethal and what it can reveal about the next outbreak from the coronavirus family.
Nature | 14 min read

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