Long non-coding RNA
Signaling in and out: long-noncoding RNAs in tumor hypoxia
Over the past few years, long non-coding RNAs (lncRNAs) are recognized as key regulators of gene expression at chromatin, transcriptional and posttranscriptional level with pivotal roles in various biological ...Journal of Biomedical Science 2020 27:59Expedition to the missing link: Long noncoding RNAs in cardiovascular diseases
With the advances in deep sequencing-based transcriptome profiling technology, it is now known that human genome is transcribed more pervasively than previously thought. Up to 90% of the human DNA is transcrib...Journal of Biomedical Science 2020 27:48Functions and properties of nuclear lncRNAs—from systematically mapping the interactomes of lncRNAs
Protein and DNA have been considered as the major components of chromatin. But beyond that, an increasing number of studies show that RNA occupies a large amount of chromatin and acts as a regulator of nuclear...Journal of Biomedical Science 2020 27:44PAN RNA: transcriptional exhaust from a viral engine
Kaposi’s sarcoma-associated herpesvirus (KSHV), also designated human herpesvirus 8 (HHV-8), has been linked to Kaposi’s sarcoma, as well as to primary effusion lymphoma (PEL), and a subset of multicentric Cas...Journal of Biomedical Science 2020 27:41Functional Roles of Long Non-coding RNAs in Motor Neuron Development and Disease
Long non-coding RNAs (lncRNAs) have gained increasing attention as they exhibit highly tissue- and cell-type specific expression patterns. LncRNAs are highly expressed in the central nervous system and their r...Journal of Biomedical Science 2020 27:38
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