miércoles, 6 de mayo de 2020

Genomic Gymnastics of a Single-Celled Ciliate and How It Relates to Humans – Biomedical Beat Blog – National Institute of General Medical Sciences

Genomic Gymnastics of a Single-Celled Ciliate and How It Relates to Humans – Biomedical Beat Blog – National Institute of General Medical Sciences

Source: Eva Mutunga and Kate Klein, University of the District of Columbia and National Institute of Standards and Technology. This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States License.​

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A black and white image of two ciliate cells mating.

Genomic Gymnastics of a Single-Celled Ciliate and How It Relates to Humans

Oxytricha trifallax cells appear to delight in genomic chaos. During sexual reproduction, the ciliate shatters the DNA in one of its two nuclei into hundreds of thousands of pieces, descrambles the DNA letters, throws most away, then recombines the rest to create a new genome. Understanding how Oxytricha rearranges its genome could illuminate some of the events that go awry during cancer.
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