CORONAVIRUS RESEARCH HIGHLIGHTS: 1-MINUTE READS
How China stopped the outbreak
Drastic social distancing in Shanghai and Wuhan was enough to bring the epidemic under control in the two cities. Modelling work suggests that, in Shanghai, school closures alone would not have stopped the epidemic — but they did lower the number of new infections per day at the epidemic’s peak, which relieved stress on hospitals. Another study shows that quick detection and isolation of infected people were the most effective steps for containing COVID-19 in China. But even with those efforts in place, the number of cases would have soared if officials hadn’t restricted travel and social interactions.
Reference: Science paper & Nature paper
Portraits of a viral enzyme could aid the hunt for drugs
Molecular snapshots of a key SARS-CoV-2 enzyme in action provide clues to how drugs, including the experimental therapy remdesivir, attack the virus. Two teams looked at the action and structure of a viral enzyme called an RNA-dependent RNA polymerase.
Reference: bioRxiv preprint & Science paper
Drastic social distancing in Shanghai and Wuhan was enough to bring the epidemic under control in the two cities. Modelling work suggests that, in Shanghai, school closures alone would not have stopped the epidemic — but they did lower the number of new infections per day at the epidemic’s peak, which relieved stress on hospitals. Another study shows that quick detection and isolation of infected people were the most effective steps for containing COVID-19 in China. But even with those efforts in place, the number of cases would have soared if officials hadn’t restricted travel and social interactions.
Reference: Science paper & Nature paper
Portraits of a viral enzyme could aid the hunt for drugs
Molecular snapshots of a key SARS-CoV-2 enzyme in action provide clues to how drugs, including the experimental therapy remdesivir, attack the virus. Two teams looked at the action and structure of a viral enzyme called an RNA-dependent RNA polymerase.
Reference: bioRxiv preprint & Science paper
Get more of Nature’s continuously updated selection of the must-read papers and preprints on COVID-19.
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