Common genetic variant explains why Crohn's immunotherapy often fails

Common genetic variant explains why Crohn's immunotherapy often fails

Common genetic variant explains why immunotherapy often fails in Crohn's disease

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By Lois Zoppi, BAOct 7 2019Reviewed by Kate Anderton, B.Sc. (Editor)

The reason why a commonly used range of drugs is not effective in some patients living with Crohn’s disease has so far not been identified. However, a collaboration between the University of Exeter, Royal Devon & Exeter NHS Foundation Trust and the Wellcome Sanger Institute has discovered a genetic marker that could lead to personalized treatments for Crohn’s cases.