Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores JR Homburger et al, BioxRIV preprints, July 31, 2019

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Last Posted: Aug 02, 2019

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• Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores
  JR Homburger et al, BioxRIV preprints, July 31, 2019
• Genetic Markers Predict Primary Nonresponse and Durable Response to Anti-Tumor Necrosis Factor Therapy in Ulcerative Colitis.
  Burke Kristin E et al. Inflammatory bowel diseases 2018 24(8) 1840-1848
• Integration of genetic and clinical information to improve imputation of data missing from electronic health records.
  Li Ruowang et al. Journal of the American Medical Informatics Association : JAMIA 2019 Apr
• Pharmacogenetics in Pain Treatment.
  Peiró Ana M et al. Advances in pharmacology (San Diego, Calif.) 2018 83247-273
• Polygenic Risk Scores in Familial Hypercholesterolemia.
  Rader Daniel J et al. Journal of the American College of Cardiology 2019 Jul 74(4) 523-525
• Psychiatric Polygenic Risk Scores as Predictor for Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in a Clinical Child and Adolescent Sample.
  Jansen Arija G et al. Behavior genetics 2019 Jul
• Risk of Premature Atherosclerotic Disease in Patients With Monogenic Versus Polygenic Familial Hypercholesterolemia.
  Trinder Mark et al. Journal of the American College of Cardiology 2019 Jul 74(4) 512-522
• Towards clinical utility of polygenic risk scores 
  SA Lambert et al, Hum Mol Genetics, July 31, 2019
• A Weighted Genetic Risk Score Based on Four APOE-Independent Alzheimer's Disease Risk Loci May Supplement APOE E4 for Better Disease Prediction.
  Zhang Chunyu et al. Journal of molecular neuroscience : MN 2019 Jul
• Genome editing, Goldilocks and polygenic risk scores.
  Savulescu Julian et al. Journal of medical ethics 2019 Jul

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