From public health genomics to precision public health: a 20-year journey

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Abstract

In this paper, we review the evolution of the field of public health genomics in the United States in the past two decades. Public health genomics focuses on effective and responsible translation of genomic science into population health benefits. We discuss the relationship of the field to the core public health functions and essential services, review its evidentiary foundation, and provide examples of current US public health priorities and applications. We cite examples of publications to illustrate how Genetics in Medicinereflected the evolution of the field. We also reflect on how public-health genomics is contributing to the emergence of “precision public health” with near-term opportunities offered by the US Precision Medicine (AllofUs) Initiative.

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From public health genomics to precision public health: a 20-year journey

Muin J. Khoury, MD, PhD,¹ M. Scott Bowen, MPH,¹ Mindy Clyne, MS,² W. David Dotson, PhD,¹ Marta L. Gwinn, MD, MPH,³ Ridgely Fisk Green, PhD,¹ Katherine Kolor, PhD,¹ Juan L. Rodriguez, PhD,⁴ Anja Wulf,¹ and Wei Yu, PhD¹

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